Heart failure with false negative BNP – Cardiology MCQ – Answer

In which of the following conditions with heart failure can false negative BNP (B-type natriuretic peptide) values occur?

Correct answer: 

3. Mitral stenosis

False negative BNP can occur in obesity, flash pulmonary edema (BNP elevation may be delayed) and mitral stenosis (heart failure without dilatation of left ventricle).

False positive BNP can occur in old age, renal failure, myocardial infarction and cor pulmonale.

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