{"id":11665,"date":"2014-06-05T15:10:09","date_gmt":"2014-06-05T15:10:09","guid":{"rendered":"http:\/\/cardiophile.org\/?p=11665"},"modified":"2014-06-05T15:10:09","modified_gmt":"2014-06-05T15:10:09","slug":"prediction-of-superresponders-to-crt","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/prediction-of-superresponders-to-crt\/","title":{"rendered":"Prediction of superresponders to CRT"},"content":{"rendered":"<h2><span style=\"color: #008000;\">Prediction of superresponders to CRT<\/span><\/h2>\n<p>Prediction of superresponders to CRT: Various types of responses are possible after implantation of a cardiac resynchronization device (CRT) in a person with heart failure. There could be no response (non-responder), good response (responder), and a super response (superresponder). Some could even have a negative response.<\/p>\n<p>Superresponders have a good clinical outcome. Those with wide QRS complex indicating extensive intraventricular conduction disease are likely to have a superresponse. They typically have a QRS duration of 150 milliseconds or more and left bundle branch block. Females and those with no previous infarction are likely to have a better response. Body mass index less than 30 kilograms per square meter and small baseline left atrial volume index may also predict a better response [1].<\/p>\n<p>As an example, the authors presented a 55 year old female who had been implanted CRT with defibrillator 6 years earlier for non ischemic dilated cardiomyopathy. He left ventricular ejection fraction prior to implantation was 28%. It increased to 38% with CRT. Her left ventricular end diastolic volume index came down from 144 mL\/m<sup>2<\/sup> to 95 mL\/m<sup>2<\/sup> and her left ventricular end systolic volume index came down from 104 mL\/m<sup>2<\/sup> to 59 mL\/m<sup>2<\/sup>.<\/p>\n<p><span style=\"color: #0000ff;\"><b>Reference<\/b><\/span><\/p>\n<ol>\n<li>Jan Steffel, Frank Ruschitzka. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24982120\/\">Superresponse to Cardiac Resynchronization Therapy<\/a>. Circulation. 2014 Jul 1;130(1):87-90.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Prediction of superresponders to CRT Prediction of superresponders to CRT: Various types of responses are possible after implantation of a cardiac resynchronization device (CRT) in a person with heart failure. There could be no response (non-responder), good response (responder), and a super response (superresponder). Some could even have a negative response. Superresponders have a good [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":34327,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[6],"tags":[],"class_list":["post-11665","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ecg-electrophysiology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prediction of superresponders to CRT:QRS 150 ms or more, LBBB pattern<\/title>\n<meta name=\"description\" content=\"Prediction of superresponders to CRT: Those with QRS complex of 150 msec or more with left bundle branch block pattern, females and no previous MI\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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