{"id":13299,"date":"2014-08-04T15:20:43","date_gmt":"2014-08-04T15:20:43","guid":{"rendered":"http:\/\/cardiophile.org\/?p=13299"},"modified":"2022-04-09T09:30:35","modified_gmt":"2022-04-09T04:00:35","slug":"tga-like-physiology","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/tga-like-physiology\/","title":{"rendered":"TGA like physiology"},"content":{"rendered":"<p><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/_N8d7ljMf0M\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<h2><span style=\"color: #008000;\">TGA like physiology \u2013 cyanotic heart disease with high pulmonary blood flow<\/span><\/h2>\n<p>Following congenital heart diseases\u00a0have cyanosis with high pulmonary blood flood flow (TGA like physiology or transposition like physiology):<\/p>\n<ol>\n<li>Dextro transposition of great arteries (D- TGA) with ventricular septal defect (VSD) and no pulmonary stenosis (PS)<\/li>\n<li>Double outlet right ventricle (DORV) with VSD and no PS<\/li>\n<li>Tricuspid atresia with VSD and no PS<\/li>\n<\/ol>\n<figure id=\"attachment_53465\" aria-describedby=\"caption-attachment-53465\" style=\"width: 1226px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-53465\" src=\"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2014\/08\/TGA-like-physiology-2.jpg\" alt=\"TGA like physiology (Diagrammatic)\" width=\"1226\" height=\"675\" srcset=\"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2014\/08\/TGA-like-physiology-2.jpg 1226w, https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2014\/08\/TGA-like-physiology-2-300x165.jpg 300w, https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2014\/08\/TGA-like-physiology-2-1024x564.jpg 1024w, https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2014\/08\/TGA-like-physiology-2-768x423.jpg 768w\" sizes=\"auto, (max-width: 1226px) 100vw, 1226px\" \/><figcaption id=\"caption-attachment-53465\" class=\"wp-caption-text\">TGA like physiology (Diagrammatic)<\/figcaption><\/figure>\n<p>TGA like physiologies can present with cyanosis and heart failure in very early life due to increased pulmonary blood flow as there is no pulmonary stenosis to restrict the pulmonary blood flow. D-TGA with VSD and no PS is a condition which can cause cyanosis on first day of life. This is in contrast to Tetralogy where the onset of cyanosis is delayed. Some of these patients may need pulmonary artery banding to reduce pulmonary blood flow if immediate surgical correction is not feasible. In case of D-TGA early surgical correction with arterial switch operation (Jatene operation) is ideal. TGA physiologies do not have hypercyanotic spells (cyanotic spells) and they do not give history of squatting which occurs in later life with TOF (tetralogy of Fallot) like physiologies.<\/p>\n<p>Atrial switch operations were described for TGA prior to arterial switch. First was Senning operation using atrial flaps in 1957 [1]. Mustard operation using pericardium was described in 1963 [2]. First successful arterial switch had to wait till 1975.<\/p>\n<p><span style=\"color: #0000ff;\"><strong>References<\/strong><\/span><\/p>\n<ol>\n<li>Senning A. Surgical correction of transposition of the great vessels. Surgery. 1959 Jun;45(6):966-80.<\/li>\n<li>Marathe SP, Talwar S. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4453180\/\">Surgery for transposition of great arteries: A historical perspective<\/a>. Ann Pediatr Cardiol. 2015 May-Aug;8(2):122-8.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>TGA like physiology can be seen in D- TGA with VSD and no PS, DORV with VSD and no PS, tricuspid atresia with VSD and no PS etc.<\/p>\n","protected":false},"author":1,"featured_media":53465,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[331,1022,1023,1033,1103,1194,1975,3097,3146,3880,4000,4023,4172,4211],"class_list":["post-13299","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","tag-arterial-switch-operation","tag-cyanotic-heart-disease","tag-cyanotic-heart-disease-with-high-pulmonary-blood-flow","tag-d-tga","tag-dextro-transposition-of-great-arteries","tag-dorv","tag-jatenes-operation","tag-ps","tag-pulmonary-stenosis","tag-tga-like-physiology","tag-transposition-like-physiology","tag-tricuspid-atresia","tag-ventricular-septal-defect","tag-vsd"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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