{"id":22148,"date":"2017-09-04T13:04:48","date_gmt":"2017-09-04T07:34:48","guid":{"rendered":"https:\/\/cardiophile.org\/?p=22148"},"modified":"2017-09-04T13:04:48","modified_gmt":"2017-09-04T07:34:48","slug":"crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/","title":{"rendered":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis"},"content":{"rendered":"

CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis<\/span><\/h2>\n

CRT-D better than CRT-P in NIDCM: Francisco Leyva and colleagues compared the outcomes of cardiac resynchronization therapy with (CRT-D) or without defibrillation (CRT-P) in non ischemic dilated cardiomyopathy<\/a> (NIDCM) [1]. Of their 252 patients, 68 had left ventricular midwall fibrosis detected by cardiac magnetic resonance imaging (CMR). It was found that left ventricular midwall fibrosis was an independent predictor of total mortality, death from pump failure and sudden cardiac death. Maximum follow up period in their study was 14 years. They documented lower total mortality or hospitalization for major adverse cardiac events in those with CRT-D compared with CRT-P in those with left ventricular midwall fibrosis. This was not observed in those without left ventricular midwall fibrosis. The finding would favour usage of CRT-D over CRT-P in NIDCM with left ventricular mid wall fibrosis.<\/p>\n

It was also noted that midwall fibrosis predicted total mortality, composite of total mortality and heart failure hospitalizations, cardiovascular mortality and a composite of total mortality or major adverse cardiovascular events [1]. Another important finding was that the association of mid wall fibrosis and total mortality was linked to pump failure as well as sudden cardiac death and hospitalization for ventricular arrhythmias. So the mid wall fibrosis was the factor associated with benefit of CRT-D over CRT-P.<\/p>\n

Reference<\/span><\/strong><\/p>\n

    \n
  1. Leyva F, Zegard A, Acquaye E, Gubran C, Taylor R, Foley PWX, Umar F, Patel K, Panting J, Marshall H, Qiu T. Outcomes of Cardiac Resynchronization Therapy With or Without Defibrillation in Patients With Nonischemic Cardiomyopathy<\/a>. J Am Coll Cardiol. 2017 Sep 5;70(10):1216-1227.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis CRT-D better than CRT-P in NIDCM: Francisco Leyva and colleagues compared the outcomes of cardiac resynchronization therapy with (CRT-D) or without defibrillation (CRT-P) in non ischemic dilated cardiomyopathy (NIDCM) [1]. Of their 252 patients, 68 had left ventricular midwall fibrosis detected by cardiac magnetic […]<\/p>\n","protected":false},"author":1,"featured_media":33402,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[6],"tags":[],"class_list":["post-22148","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ecg-electrophysiology"],"yoast_head":"\nCRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"description\" content=\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2017-09-04T07:34:48+00:00\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis\",\"datePublished\":\"2017-09-04T07:34:48+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/\"},\"wordCount\":271,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"articleSection\":[\"ECG \\\/ Electrophysiology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/\",\"name\":\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"datePublished\":\"2017-09-04T07:34:48+00:00\",\"description\":\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#primaryimage\",\"url\":\"\",\"contentUrl\":\"\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\",\"name\":\"All About Cardiovascular System and Disorders\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\",\"name\":\"Johnson Francis\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"caption\":\"Johnson Francis\"},\"logo\":{\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\"},\"description\":\"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/author\\\/jf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders","description":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/","og_locale":"en_US","og_type":"article","og_title":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders","og_description":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.","og_url":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/","og_site_name":"All About Cardiovascular System and Disorders","article_published_time":"2017-09-04T07:34:48+00:00","author":"Johnson Francis","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Johnson Francis","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#article","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/"},"author":{"name":"Johnson Francis","@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"headline":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis","datePublished":"2017-09-04T07:34:48+00:00","mainEntityOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/"},"wordCount":271,"publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#primaryimage"},"thumbnailUrl":"","articleSection":["ECG \/ Electrophysiology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/","url":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/","name":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis - All About Cardiovascular System and Disorders","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#website"},"primaryImageOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#primaryimage"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#primaryimage"},"thumbnailUrl":"","datePublished":"2017-09-04T07:34:48+00:00","description":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis: lower total mortality or hospitalization for MACE with CRT-D compared with CRT-P.","breadcrumb":{"@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#primaryimage","url":"","contentUrl":""},{"@type":"BreadcrumbList","@id":"https:\/\/johnsonfrancis.org\/professional\/crt-d-better-than-crt-p-in-nidcm-with-left-ventricular-midwall-fibrosis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/johnsonfrancis.org\/professional\/"},{"@type":"ListItem","position":2,"name":"CRT-D better than CRT-P in NIDCM with left ventricular midwall fibrosis"}]},{"@type":"WebSite","@id":"https:\/\/johnsonfrancis.org\/professional\/#website","url":"https:\/\/johnsonfrancis.org\/professional\/","name":"All About Cardiovascular System and Disorders","description":"","publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/johnsonfrancis.org\/professional\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":["Person","Organization"],"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec","name":"Johnson Francis","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","caption":"Johnson Francis"},"logo":{"@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g"},"description":"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal","url":"https:\/\/johnsonfrancis.org\/professional\/author\/jf\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/22148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/comments?post=22148"}],"version-history":[{"count":0,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/22148\/revisions"}],"wp:attachment":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/media?parent=22148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/categories?post=22148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/tags?post=22148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}