{"id":22932,"date":"2018-01-15T19:52:12","date_gmt":"2018-01-15T14:22:12","guid":{"rendered":"https:\/\/cardiophile.org\/?p=22932"},"modified":"2022-11-26T18:52:06","modified_gmt":"2022-11-26T13:22:06","slug":"cardiovascular-causes-of-stroke","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/cardiovascular-causes-of-stroke\/","title":{"rendered":"Cardiovascular causes of stroke"},"content":{"rendered":"<p><iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/vCYMQwgKRhU\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\"><\/iframe><\/p>\n<h2><span style=\"color: #008000;\">Cardiovascular causes of stroke<\/span><\/h2>\n<p>Here are some important cardiovascular causes of stroke include:<\/p>\n<ol>\n<li>\n<p align=\"LEFT\">Atrial fibrillation \/ flutter<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Patent foramen ovale (PFO) with right to left shunt or atrial septal aneurysm<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Cardiomyopathy<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Aortic arch atheroma<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Valvular heart disease with intracardiac thrombi or vegetations<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Atrial myxoma and fibroelastoma<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Mural thrombus in myocardial infarction<\/p>\n<\/li>\n<\/ol>\n<p align=\"LEFT\">Two recent trials (Gore REDUCE and CLOSE) [1,2] and long term outcome results of RESPECT trial [3] provide clear evidence for PFO closure for stroke prevention in those below 60 years with high risk \u2013 PFO. High risk PFO is one with substantial right to left shunting or an atrial septal aneurysm.<\/p>\n<p align=\"LEFT\"><strong><span style=\"color: #0000ff;\">References<\/span><\/strong><\/p>\n<ol>\n<li>\n<p align=\"LEFT\">Sondergaard L, Kasner SE, Rhodes JF, Andersen G, Iversen HK, Nielsen-Kudsk JE, Settergren M, Sjostrand C, Roine RO, Hildick-Smith D, Spence JD, Thomassen L; Gore REDUCE Clinical Study Investigators. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28902580\">Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke<\/a>. N Engl J Med. 2017;377:1033\u20131042.<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, Arquizan C, Bejot Y, Vuillier F, Detante O, Guidoux C, Canaple S, Vaduva C, Dequatre-Ponchelle N, Sibon I, Garnier P, Ferrier A, Timsit S, Robinet-Borgomano E, Sablot D, Lacour JC, Zuber M, Favrole P, Pinel JF, Apoil M, Reiner P, Lefebvre C, Gu\u00e9rin P, Piot C, Rossi R, Dubois-Rand\u00e9 JL, Eicher JC, Meneveau N, Lusson JR, Bertrand B, Schleich JM, Godart F, Thambo JB, Leborgne L, Michel P, Pierard L, Turc G, Barthelet M, Charles-Nelson A, Weimar C, Moulin T, Juliard JM, Chatellier G; CLOSE Investigators. Patent foramen ovale closure or anticoagulation vs. antiplatelets after stroke. N Engl J Med. 2017;377:1011\u20131021.<\/p>\n<\/li>\n<li>\n<p align=\"LEFT\">Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS, Tirschwell DL; RESPECT Investigators. Long-term outcomes of patent foramen ovale closure or medical therapy after stroke. N Engl J Med. 2017;377:1022\u20131032.<\/p>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Cardiovascular causes of stroke: AF, patent foramen ovale (PFO) with right to left shunt or atrial septal aneurysm, cardiomyopathy, aortic arch atheroma, valvular heart disease with intracardiac thrombi or vegetations, atrial myxoma and fibroelastoma, and mural thrombus in myocardial infarction<\/p>\n","protected":false},"author":1,"featured_media":40145,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-22932","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cardiovascular causes of stroke: AF, PFO with R-L shunt, thrombi etc<\/title>\n<meta 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