{"id":31090,"date":"2020-04-14T11:58:46","date_gmt":"2020-04-14T06:28:46","guid":{"rendered":"https:\/\/johnsonfrancis.org\/professional\/?p=31090"},"modified":"2020-04-14T11:58:46","modified_gmt":"2020-04-14T06:28:46","slug":"scores-predicting-bleeding-risk-in-af","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/scores-predicting-bleeding-risk-in-af\/","title":{"rendered":"Scores predicting bleeding risk in AF"},"content":{"rendered":"<p><iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/xJpHUAN7gwc\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\"><\/iframe><\/p>\n<h2><span style=\"color: #008000;\">Scores predicting bleeding risk in AF<\/span><\/h2>\n<p>Anticoagulation is vital for reducing the risk of stroke in atrial fibrillation (AF). There are several scores predicting bleeding risk in AF. These can be used to weigh between the need for anticoagulation and the risk of bleeding with it while taking an individualized decision.<\/p>\n<p><a href=\"https:\/\/johnsonfrancis.org\/professional\/management-of-atrial-fibrillation-based-on-guidelines-part-ii\/#HAS-BLED\">HAS-BLED<\/a>: Hypertension, Abnormal liver or renal function, Stroke, Bleeding, Labile INRs, Elderly (&gt;65 years), Drugs or Ethanol Abuse (1 point each). Maximum score possible is 9.<\/p>\n<p>HEMORR<sub>2<\/sub>HAGES: (Hepatic or Renal Disease, Ethanol Abuse, Malignancy History, Older than age 75, Reduced platelet count or function, Rebleeding risk, Hypertension, Anemia, Genetic factors (CYP2C9 single nucleotide polymorphisms), Excessive fall risk, Stroke history<\/p>\n<p>ATRIA: Anemia, severe renal disease, Age 75 or older, Any prior hemorrhage diagnosis, Hypertension history<\/p>\n<p>ORBIT: Outcomes Registry for Better Informed Treatment<\/p>\n<p>In a post hoc analysis of clinically relevant and major bleeding in the around 2300 patients on warfarin in the AMADEUS trial, HAS-BLED score was shown to be better performing than ATRIA and ORBIT scores [1]. They could improve the predictive value of ATRIA and ORBIT by adding the time in therapeutic range (TTR) of warfarin to the scores.<\/p>\n<p><span style=\"color: #0000ff;\"><strong>References<\/strong><\/span><\/p>\n<ol>\n<li>Senoo K, Proietti M, Lane DA, Lip GY. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26482233\">Evaluation of the HAS-BLED, ATRIA, and ORBIT Bleeding Risk Scores in Patients with Atrial Fibrillation Taking Warfarin<\/a>. Am J Med. 2016 Jun;129(6):600-7<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Scores predicting bleeding risk in AF Anticoagulation is vital for reducing the risk of stroke in atrial fibrillation (AF). There are several scores predicting bleeding risk in AF. These can be used to weigh between the need for anticoagulation and the risk of bleeding with it while taking an individualized decision. HAS-BLED: Hypertension, Abnormal liver [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[2],"tags":[],"class_list":["post-31090","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cardiology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Scores predicting bleeding risk in AF - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"description\" content=\"Important scores predicting bleeding risk in AF are HAS-BLED, HEMORR2HAGES, ATRIA and ORBIT. HAS-BLED score performed better than ATRIA and ORBIT.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/scores-predicting-bleeding-risk-in-af\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scores predicting bleeding risk in AF - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"Important scores predicting bleeding risk in AF are HAS-BLED, HEMORR2HAGES, ATRIA and ORBIT. HAS-BLED score performed better than ATRIA and ORBIT.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/scores-predicting-bleeding-risk-in-af\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2020-04-14T06:28:46+00:00\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"Scores predicting bleeding risk in AF\",\"datePublished\":\"2020-04-14T06:28:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/\"},\"wordCount\":224,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"articleSection\":[\"Cardiology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/\",\"name\":\"Scores predicting bleeding risk in AF - All About Cardiovascular System and Disorders\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/scores-predicting-bleeding-risk-in-af\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"datePublished\":\"2020-04-14T06:28:46+00:00\",\"description\":\"Important scores predicting bleeding risk in AF are HAS-BLED, HEMORR2HAGES, ATRIA and ORBIT. 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