{"id":4597,"date":"2010-05-17T15:03:57","date_gmt":"2010-05-17T15:03:57","guid":{"rendered":"http:\/\/cardiophile.org\/?p=4597"},"modified":"2010-05-17T15:03:57","modified_gmt":"2010-05-17T15:03:57","slug":"high-sensitivity-c-reactive-protein-hs-crp","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/high-sensitivity-c-reactive-protein-hs-crp\/","title":{"rendered":"High sensitivity C-reactive protein (hs-CRP)"},"content":{"rendered":"

High sensitivity C-reactive protein (hs-CRP)<\/span><\/h2>\n

High sensitivity C-reactive protein (hs-CRP): 2009 Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult has recognized high sensitivity C-reactive protein (hs-CRP) as a major cardiovascular risk factor. According to the American Heart Association levels of hs-CRP lower than 1.0 mg\/dl indicate low risk of developing cardiovascular disease while levels higher than 3.0 mg\/dl indicates high risk. The risk is moderate with levels in between. In the JUPITER trial, those with hs-CRP more than 2 mg\/dl, but otherwise low risk, when given 20 mg of rosuvastatin, had a 44% reduction in major vascular events, 54% reduction in myocardial infarction, 48% reduction in stroke, 46% reduction in the need for angioplasty or bypass surgery and 20% reduction in all-cause mortality. Similar risk reduction was seen in those with Framingham Risk Scores of 5% to 10% (6,091 persons) as well as in those with Framingham Risk Scores of 11% to 20% (7,340 persons). A recent meta-analysis of 9 studies involving more than a thousand patients have found that in stent restenosis is higher in those with elevated hs-CRP [1].<\/p>\n

Reference<\/span><\/strong><\/p>\n

    \n
  1. Jian-Jun Li, Yi Ren, Ke-Ji Chen, Alan C Yeung, Bo Xu, Xin-Min Ruan, Yue-Jin Yang, Ji-Lin Chen, Run-Lin Gao. Impact of C-reactive protein on in-stent restenosis: a meta-analysis<\/a>. Tex Heart Inst J 2010;37:49\u201357.<\/li>\n<\/ol>\n\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    2009 Canadian Cardiovascular Society guidelines has recognized high sensitivity C-reactive protein (hs-CRP) as a major cardiovascular risk factor.<\/p>\n","protected":false},"author":1,"featured_media":38842,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-4597","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"\nHigh sensitivity C-reactive protein (hs-CRP)<\/title>\n<meta name=\"description\" content=\"2009 Canadian Cardiovascular Society guidelines has recognized high sensitivity C-reactive protein (hs-CRP) as a major cardiovascular risk factor.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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