{"id":63915,"date":"2025-07-05T21:58:52","date_gmt":"2025-07-05T16:28:52","guid":{"rendered":"https:\/\/johnsonfrancis.org\/professional\/?p=63915"},"modified":"2025-07-05T21:58:55","modified_gmt":"2025-07-05T16:28:55","slug":"clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/","title":{"rendered":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease"},"content":{"rendered":"<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/dxu7CbYUIxs?si=4oxWu_UpaptVW1VJ\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n\n<p class=\"wp-block-paragraph\">Clonal hematopoiesis of indeterminate potential (CHIP) is due to somatic mutations which cause expansion of hematopoietic stem cells. This is in the absence of overt hematologic malignancy. CHIP is more common in the elderly and increases cardiovascular risk independent of traditional risk factors. There is also an increased risk for development of hematological malignancies. There is an association of a pro-inflammatory state with CHIP which has been linked to coronary artery disease, myocardial infarction, venous thromboembolism and prognosis in those with aortic stenosis and heart failure [1]. CHIP may have\u00a0implications for risk prediction and mitigation [2].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">338 patients in the <a href=\"https:\/\/johnsonfrancis.org\/professional\/cantos-trial-of-canakinumab\/\">CANTOS trial of canakinumab<\/a> had evidence for clonal hematopoiesis [3]. As expected, patients with CHIP were older, with a mean age of 66.3 years compared to 61.5 years in those without CHIP. Placebo treated patients with CHIP had a nonsignificant increase in the rate of major adverse cardiovascular events compared to those without CHIP. Patients on canakinumab with CHIP due to somatic variants in TET2 gene showed a reduced risk of MACE. Thus there is an indication of the role of inflammation in these patients. CANTOS trial had selected patients with elevated C-reactive protein for randomization.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>References<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li class=\"\">Marnell CS, Bick A, Natarajan P. Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease. J Mol Cell Cardiol. 2021 Dec;161:98-105. doi: 10.1016\/j.yjmcc.2021.07.004. Epub 2021 Jul 21. PMID: 34298011; PMCID: PMC8629838.<\/li>\n\n\n\n<li class=\"\">Khetarpal SA, Qamar A, Bick AG, Fuster JJ, Kathiresan S, Jaiswal S, Natarajan P. Clonal Hematopoiesis of Indeterminate\u00a0Potential Reshapes Age-Related CVD: JACC Review Topic of the Week. J Am Coll Cardiol. 2019 Jul 30;74(4):578-586. doi: 10.1016\/j.jacc.2019.05.045. PMID: 31345433; PMCID: PMC6662618.<\/li>\n\n\n\n<li class=\"\">Svensson EC, Madar A, Campbell CD, He Y, Sultan M, Healey ML, Xu H, D&#8217;Aco K, Fernandez A, Wache-Mainier C, Libby P, Ridker PM, Beste MT, Basson CT. TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial. JAMA Cardiol. 2022 May 1;7(5):521-528. doi: 10.1001\/jamacardio.2022.0386. PMID: 35385050; PMCID: PMC8988022.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Clonal hematopoiesis of indeterminate potential (CHIP) is due to somatic mutations which cause expansion of hematopoietic stem cells. This is in the absence of overt hematologic malignancy. CHIP is more common in the elderly and increases cardiovascular risk independent of traditional risk factors. There is also an increased risk for development of hematological malignancies. There [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":63918,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-63915","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"Clonal hematopoiesis of indeterminate potential (CHIP) is due to somatic mutations which cause expansion of hematopoietic stem cells. This is in the absence of overt hematologic malignancy. CHIP is more common in the elderly and increases cardiovascular risk independent of traditional risk factors. There is also an increased risk for development of hematological malignancies. There [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-05T16:28:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-05T16:28:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"679\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease\",\"datePublished\":\"2025-07-05T16:28:52+00:00\",\"dateModified\":\"2025-07-05T16:28:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/\"},\"wordCount\":331,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg\",\"articleSection\":[\"General Cardiology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/\",\"name\":\"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg\",\"datePublished\":\"2025-07-05T16:28:52+00:00\",\"dateModified\":\"2025-07-05T16:28:55+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#primaryimage\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg\",\"contentUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg\",\"width\":1200,\"height\":679},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\",\"name\":\"All About Cardiovascular System and Disorders\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\",\"name\":\"Johnson Francis\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"caption\":\"Johnson Francis\"},\"logo\":{\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\"},\"description\":\"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/author\\\/jf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/","og_locale":"en_US","og_type":"article","og_title":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders","og_description":"Clonal hematopoiesis of indeterminate potential (CHIP) is due to somatic mutations which cause expansion of hematopoietic stem cells. This is in the absence of overt hematologic malignancy. CHIP is more common in the elderly and increases cardiovascular risk independent of traditional risk factors. There is also an increased risk for development of hematological malignancies. There [&hellip;]","og_url":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/","og_site_name":"All About Cardiovascular System and Disorders","article_published_time":"2025-07-05T16:28:52+00:00","article_modified_time":"2025-07-05T16:28:55+00:00","og_image":[{"width":1200,"height":679,"url":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg","type":"image\/jpeg"}],"author":"Johnson Francis","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Johnson Francis","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#article","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/"},"author":{"name":"Johnson Francis","@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"headline":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease","datePublished":"2025-07-05T16:28:52+00:00","dateModified":"2025-07-05T16:28:55+00:00","mainEntityOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/"},"wordCount":331,"publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg","articleSection":["General Cardiology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/","url":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/","name":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease - All About Cardiovascular System and Disorders","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#website"},"primaryImageOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#primaryimage"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg","datePublished":"2025-07-05T16:28:52+00:00","dateModified":"2025-07-05T16:28:55+00:00","breadcrumb":{"@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#primaryimage","url":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg","contentUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Clonal-hematopoiesis-of-indeterminate-potential-CHIP-and-cardiovascular-disease.jpg","width":1200,"height":679},{"@type":"BreadcrumbList","@id":"https:\/\/johnsonfrancis.org\/professional\/clonal-hematopoiesis-of-indeterminate-potential-chip-and-cardiovascular-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/johnsonfrancis.org\/professional\/"},{"@type":"ListItem","position":2,"name":"Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease"}]},{"@type":"WebSite","@id":"https:\/\/johnsonfrancis.org\/professional\/#website","url":"https:\/\/johnsonfrancis.org\/professional\/","name":"All About Cardiovascular System and Disorders","description":"","publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/johnsonfrancis.org\/professional\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":["Person","Organization"],"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec","name":"Johnson Francis","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","caption":"Johnson Francis"},"logo":{"@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g"},"description":"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal","url":"https:\/\/johnsonfrancis.org\/professional\/author\/jf\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/comments?post=63915"}],"version-history":[{"count":3,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63915\/revisions"}],"predecessor-version":[{"id":63919,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63915\/revisions\/63919"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/media\/63918"}],"wp:attachment":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/media?parent=63915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/categories?post=63915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/tags?post=63915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}