{"id":63973,"date":"2025-07-15T10:56:35","date_gmt":"2025-07-15T05:26:35","guid":{"rendered":"https:\/\/johnsonfrancis.org\/professional\/?p=63973"},"modified":"2025-07-15T10:56:40","modified_gmt":"2025-07-15T05:26:40","slug":"categories-of-biomarkers-according-to-fda-nih-best","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/","title":{"rendered":"Categories of Biomarkers according to FDA-NIH BEST"},"content":{"rendered":"<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/0QKRPuRt82Y?si=hJKrGmWIX35W6CBE\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27010052\/\">BEST<\/a> (Biomarkers, EndpointS, and other Tools) Resource is a FDA-NIH Joint Leadership Council initiative. The various categories of biomarkers considered include: <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Diagnostic Biomarker<br>Monitoring Biomarker<br>Multicomponent Biomarker<br>Predictive Biomarker<br>Prognostic Biomarker<br>Response Biomarker<br>Safety Biomarker<br>Susceptibility\/Risk Biomarker<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A discussion of some of those relevant to cardiology with examples follows. There is some deviation from our conventional understanding of biomarkers in this concept by FDA-NIH BEST, initiated in 2016 and last updated January 7, 2025. This has also been cited in Braunwald Textbook of Heart Disease 12th Edition.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Diagnostic biomarker is used to detect or confirm presence of a disease or condition of interest or to identify individuals with a subtype of the disease. Interestingly, according to this, even ejection fraction is a diagnostic biomarker in patients with heart failure! I presume that cardiac troponins and B-type natriuretic peptides will also come under this category as well as under some other categories.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Monitoring biomarker is measured repeatedly for assessing status of a disease or medical condition or for evidence of exposure to (or effect of) a medical product or an environmental agent. International normalized ratio (INR) or prothrombin time (PT) is a monitoring biomarker in this context.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Prognostic biomarker is used to identify likelihood of a clinical event, disease recurrence or progression in patients who have the disease or medical condition of interest. C-reactive protein level may be used as a prognostic biomarker to identify patients with unstable angina or myocardial infarction with a greater likelihood of recurrent coronary artery disease events.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Safety biomarker is measured before or after an exposure to a medical product or an environmental agent to indicate the likelihood, presence, or extent of toxicity as an adverse effect. Serum potassium may be used as a safety biomarker when evaluating patients on diuretics (decreased levels), angiotensin-converting-enzyme  inhibitors, angiotensin receptor blockers, or aldosterone antagonists (increased levels). Corrected QT interval (QTc) may be used as a safety biomarker to assess the potential for drugs to induce torsades de pointes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Susceptibility\/Risk Biomarker is one that indicates the potential for developing a disease or medical condition in an individual who does not currently have clinically apparent disease or the medical condition. Factor V Leiden may be used as a susceptibility\/risk biomarker to identify individuals with a predisposition to develop deep vein thrombosis. C-reactive protein level may be used as a susceptibility\/risk biomarker to identify adult patients with a greater likelihood of incident coronary disease. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Please note that this is not a list of all biomarkers used in cardiology, just a pointer to a relatively new concept.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BEST (Biomarkers, EndpointS, and other Tools) Resource is a FDA-NIH Joint Leadership Council initiative. The various categories of biomarkers considered include: Diagnostic BiomarkerMonitoring BiomarkerMulticomponent BiomarkerPredictive BiomarkerPrognostic BiomarkerResponse BiomarkerSafety BiomarkerSusceptibility\/Risk Biomarker A discussion of some of those relevant to cardiology with examples follows. There is some deviation from our conventional understanding of biomarkers in this concept [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":63975,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-63973","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"BEST (Biomarkers, EndpointS, and other Tools) Resource is a FDA-NIH Joint Leadership Council initiative. The various categories of biomarkers considered include: Diagnostic BiomarkerMonitoring BiomarkerMulticomponent BiomarkerPredictive BiomarkerPrognostic BiomarkerResponse BiomarkerSafety BiomarkerSusceptibility\/Risk Biomarker A discussion of some of those relevant to cardiology with examples follows. There is some deviation from our conventional understanding of biomarkers in this concept [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-15T05:26:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-15T05:26:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"Categories of Biomarkers according to FDA-NIH BEST\",\"datePublished\":\"2025-07-15T05:26:35+00:00\",\"dateModified\":\"2025-07-15T05:26:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/\"},\"wordCount\":425,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg\",\"articleSection\":[\"General Cardiology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/\",\"name\":\"Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg\",\"datePublished\":\"2025-07-15T05:26:35+00:00\",\"dateModified\":\"2025-07-15T05:26:40+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#primaryimage\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg\",\"contentUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg\",\"width\":1200,\"height\":675},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/categories-of-biomarkers-according-to-fda-nih-best\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Categories of Biomarkers according to FDA-NIH BEST\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/\",\"name\":\"All About Cardiovascular System and Disorders\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\",\"name\":\"Johnson Francis\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\",\"caption\":\"Johnson Francis\"},\"logo\":{\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g\"},\"description\":\"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/author\\\/jf\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/","og_locale":"en_US","og_type":"article","og_title":"Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders","og_description":"BEST (Biomarkers, EndpointS, and other Tools) Resource is a FDA-NIH Joint Leadership Council initiative. The various categories of biomarkers considered include: Diagnostic BiomarkerMonitoring BiomarkerMulticomponent BiomarkerPredictive BiomarkerPrognostic BiomarkerResponse BiomarkerSafety BiomarkerSusceptibility\/Risk Biomarker A discussion of some of those relevant to cardiology with examples follows. There is some deviation from our conventional understanding of biomarkers in this concept [&hellip;]","og_url":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/","og_site_name":"All About Cardiovascular System and Disorders","article_published_time":"2025-07-15T05:26:35+00:00","article_modified_time":"2025-07-15T05:26:40+00:00","og_image":[{"width":1200,"height":675,"url":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg","type":"image\/jpeg"}],"author":"Johnson Francis","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Johnson Francis","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#article","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/"},"author":{"name":"Johnson Francis","@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"headline":"Categories of Biomarkers according to FDA-NIH BEST","datePublished":"2025-07-15T05:26:35+00:00","dateModified":"2025-07-15T05:26:40+00:00","mainEntityOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/"},"wordCount":425,"publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#primaryimage"},"thumbnailUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg","articleSection":["General Cardiology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/","url":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/","name":"Categories of Biomarkers according to FDA-NIH BEST - All About Cardiovascular System and Disorders","isPartOf":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#website"},"primaryImageOfPage":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#primaryimage"},"image":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#primaryimage"},"thumbnailUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg","datePublished":"2025-07-15T05:26:35+00:00","dateModified":"2025-07-15T05:26:40+00:00","breadcrumb":{"@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#primaryimage","url":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg","contentUrl":"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/07\/Categories-of-Biomarkers-according-to-FDA-NIH-BEST.jpg","width":1200,"height":675},{"@type":"BreadcrumbList","@id":"https:\/\/johnsonfrancis.org\/professional\/categories-of-biomarkers-according-to-fda-nih-best\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/johnsonfrancis.org\/professional\/"},{"@type":"ListItem","position":2,"name":"Categories of Biomarkers according to FDA-NIH BEST"}]},{"@type":"WebSite","@id":"https:\/\/johnsonfrancis.org\/professional\/#website","url":"https:\/\/johnsonfrancis.org\/professional\/","name":"All About Cardiovascular System and Disorders","description":"","publisher":{"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/johnsonfrancis.org\/professional\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":["Person","Organization"],"@id":"https:\/\/johnsonfrancis.org\/professional\/#\/schema\/person\/5441d907049b914770f4bd98fb57feec","name":"Johnson Francis","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g","caption":"Johnson Francis"},"logo":{"@id":"https:\/\/secure.gravatar.com\/avatar\/80861b82c3f559be9e413245c5643b6c483c93495507facfe32cf96ccd8bcffd?s=96&d=mm&r=g"},"description":"Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal","url":"https:\/\/johnsonfrancis.org\/professional\/author\/jf\/"}]}},"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63973","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/comments?post=63973"}],"version-history":[{"count":5,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63973\/revisions"}],"predecessor-version":[{"id":63984,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/posts\/63973\/revisions\/63984"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/media\/63975"}],"wp:attachment":[{"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/media?parent=63973"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/categories?post=63973"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/johnsonfrancis.org\/professional\/wp-json\/wp\/v2\/tags?post=63973"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}