{"id":64769,"date":"2025-09-23T16:15:14","date_gmt":"2025-09-23T10:45:14","guid":{"rendered":"https:\/\/johnsonfrancis.org\/professional\/?p=64769"},"modified":"2025-09-23T16:15:17","modified_gmt":"2025-09-23T10:45:17","slug":"what-is-the-link-between-obesity-and-sudden-death","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/what-is-the-link-between-obesity-and-sudden-death\/","title":{"rendered":"What is the link between obesity and sudden death?"},"content":{"rendered":"<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/Bi2ouQUIkqg?si=N6KERnBRKlJAawCy\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n\n<p class=\"wp-block-paragraph\">Increased body mass index has been associated with increased risk of sudden cardiac death. For every five unit increase in BMI there is an associated 16% increased risk of SCD. Though the highest risk is among those with high BMI, higher risk has also been noted in those with low BMI, suggesting a J-curve phenomenon. Those with normal BMI have the lowest risk of SCD [1]. Seattle Proportional Risk Model evaluated 9885 patients with heart failure without implantable defibrillators, of whom 2552 died during an average follow-up of 2.3 years. They found that higher body mass index was independently associated with a greater proportional risk of sudden death [2].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Visceral obesity has a stronger risk for SCD than elevated BMI. A 0.1 unit increase in waist hip ratio was associated with 82% increased risk of sudden cardiac death. Increased risk of SCD with visceral obesity is noted in both males and females [3]. Nurses Health Study documented that abdominal obesity was strongly associated with all cause and cardiovascular mortality in addition to increased cancer mortality [4]. Obesity is an important risk factor for SCD independent of conventional cardiovascular risk factors. A study of over ten thousand middle aged subjects found that body mass index of 30 or more was associated with 79% increase in risk of SCD after adjustment for age, gender, smoking, blood pressure, diabetes, cholesterol, baseline cardiac disease and ECG abnormalities [5,6].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>References<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li class=\"\">Aune D, Schlesinger S, Norat T, Riboli E. Body mass index, abdominal fatness, and the risk of sudden cardiac death: a systematic review and dose-response meta-analysis of prospective studies. Eur J Epidemiol. 2018 Aug;33(8):711-722. doi: 10.1007\/s10654-017-0353-9. Epub 2018 Feb 7. PMID: 29417316; PMCID: PMC6061127.<\/li>\n\n\n\n<li class=\"\">Shadman R, Poole JE, Dardas TF, Mozaffarian D, Cleland JG, Swedberg K, Maggioni AP, Anand IS, Carson PE, Miller AB, Levy WC. A novel method to predict the proportional risk of sudden cardiac death in heart failure: Derivation of the Seattle Proportional Risk Model. Heart Rhythm. 2015 Oct;12(10):2069-77. doi: 10.1016\/j.hrthm.2015.06.039. Epub 2015 Jun 30. PMID: 26142301.<\/li>\n\n\n\n<li class=\"\">Aune D, Schlesinger S, Norat T, Riboli E. Body mass index, abdominal fatness, and the risk of sudden cardiac death: a systematic review and dose-response meta-analysis of prospective studies. Eur J Epidemiol. 2018 Aug;33(8):711-722. doi: 10.1007\/s10654-017-0353-9. Epub 2018 Feb 7. PMID: 29417316; PMCID: PMC6061127.<\/li>\n\n\n\n<li class=\"\">Zhang C, Rexrode KM, van Dam RM, Li TY, Hu FB. Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women. Circulation. 2008 Apr 1;117(13):1658-67. doi: 10.1161\/CIRCULATIONAHA.107.739714. Epub 2008 Mar 24. PMID: 18362231.<\/li>\n\n\n\n<li class=\"\">Holmstrom L, Junttila J, Chugh SS. Sudden Death in Obesity: Mechanisms and Management. J Am Coll Cardiol. 2024 Dec 3;84(23):2308-2324. doi: 10.1016\/j.jacc.2024.09.016. Epub 2024 Nov 6. PMID: 39503654.<\/li>\n\n\n\n<li class=\"\">Eranti A, Aro AL, Kerola T, Tikkanen JT, Rissanen HA, Anttonen O, Junttila MJ, Knekt P, Huikuri HV. Body Mass Index as a Predictor of Sudden Cardiac Death and Usefulness of the Electrocardiogram for Risk Stratification. Am J Cardiol. 2016 Feb 1;117(3):388-93. doi: 10.1016\/j.amjcard.2015.10.057. Epub 2015 Nov 18. PMID: 26723105.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Increased body mass index has been associated with increased risk of sudden cardiac death. For every five unit increase in BMI there is an associated 16% increased risk of SCD. Though the highest risk is among those with high BMI, higher risk has also been noted in those with low BMI, suggesting a J-curve phenomenon. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":64777,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-64769","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>What is the link between obesity and sudden death? - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/what-is-the-link-between-obesity-and-sudden-death\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is the link between obesity and sudden death? - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"Increased body mass index has been associated with increased risk of sudden cardiac death. For every five unit increase in BMI there is an associated 16% increased risk of SCD. Though the highest risk is among those with high BMI, higher risk has also been noted in those with low BMI, suggesting a J-curve phenomenon. [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/what-is-the-link-between-obesity-and-sudden-death\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-23T10:45:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-23T10:45:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/johnsonfrancis.org\/professional\/wp-content\/uploads\/2025\/09\/What-is-the-link-between-Obesity-and-Sudden-Death.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1206\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"What is the link between obesity and sudden death?\",\"datePublished\":\"2025-09-23T10:45:14+00:00\",\"dateModified\":\"2025-09-23T10:45:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/\"},\"wordCount\":482,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/wp-content\\\/uploads\\\/2025\\\/09\\\/What-is-the-link-between-Obesity-and-Sudden-Death.jpg\",\"articleSection\":[\"General Cardiology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/what-is-the-link-between-obesity-and-sudden-death\\\/\",\"name\":\"What is the link between obesity and sudden death? 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