{"id":67941,"date":"2026-10-23T05:43:26","date_gmt":"2026-10-23T00:13:26","guid":{"rendered":"https:\/\/johnsonfrancis.org\/professional\/?p=67941"},"modified":"2026-10-23T16:46:19","modified_gmt":"2026-10-23T11:16:19","slug":"new-series-of-interactive-cardiology-mcqs-6","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/new-series-of-interactive-cardiology-mcqs-6\/","title":{"rendered":"New Series of Interactive Cardiology MCQs 6"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<!-- Cardiology MCQs Part 6 (Full 25 Questions) - WordPress Safe Custom HTML Block -->\n<script src=\"https:\/\/cdn.tailwindcss.com?plugins=forms,typography,aspect-ratio\"><\/script>\n<script>\n  tailwind.config = {\n    corePlugins: {\n      preflight: false,\n    }\n  }\n<\/script>\n\n<div id=\"mcq6-quiz-wrapper\" class=\"font-sans bg-slate-950 text-slate-100 p-4 md:p-8 rounded-3xl max-w-4xl mx-auto shadow-2xl relative overflow-hidden my-8 border border-solid border-purple-500\/20\" style=\"box-sizing: border-box;\">\n  \n  <!-- Background Accents -->\n  <div class=\"absolute top-0 left-0 w-full h-full pointer-events-none opacity-10 bg-[radial-gradient(ellipse_at_center,_var(--tw-gradient-stops))] from-blue-500 via-indigo-900 to-slate-950\"><\/div>\n  \n  <!-- Header Banner -->\n  <div class=\"relative text-center pb-6 border-b border-solid border-purple-500\/25 mb-8\">\n    <div class=\"inline-block bg-gradient-to-r from-red-600 via-pink-600 to-purple-600 text-white font-black text-xs md:text-sm px-4 py-1.5 rounded-full uppercase tracking-wider shadow-lg mb-3 animate-pulse\">\n      \u2764\ufe0f Advanced Cardiology Series &#8211; Part 6\n    <\/div>\n    <h1 class=\"text-3xl md:text-5xl font-extrabold tracking-tight text-transparent bg-clip-text bg-gradient-to-r from-cyan-300 via-blue-400 to-indigo-400 m-0\">\n      Interactive Cardiology MCQs #6\n    <\/h1>\n    <p class=\"text-sm md:text-lg text-slate-300 mt-2 max-w-2xl mx-auto font-medium\">\n      Post-Graduate Level Clinical &#038; Hemodynamic Masterclass\n    <\/p>\n  <\/div>\n\n  <!-- Real-Time Floating Scoreboard -->\n  <div class=\"sticky top-4 z-40 bg-slate-900\/90 backdrop-blur-md border-2 border-solid border-blue-500\/40 rounded-2xl p-4 mb-8 shadow-xl flex flex-wrap items-center justify-between gap-4\">\n    <div class=\"flex items-center gap-3\">\n      <div class=\"text-3xl\">\ud83c\udfc6<\/div>\n      <div>\n        <div class=\"text-[10px] uppercase font-extrabold tracking-widest text-blue-300\">Live Scoreboard<\/div>\n        <div class=\"text-lg md:text-2xl font-black text-cyan-300 flex items-center gap-1\">\n          <span id=\"mcq6-correct-count\">0<\/span><span class=\"text-slate-500 text-sm md:text-lg\">\/ 25 Correct<\/span>\n        <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"flex items-center gap-2 bg-slate-950\/80 px-4 py-2 rounded-xl border border-solid border-slate-800\">\n      <span class=\"text-xs font-bold text-slate-400 uppercase tracking-wider\">Progress:<\/span>\n      <div class=\"w-24 md:w-36 bg-slate-800 h-3 rounded-full overflow-hidden\">\n        <div id=\"mcq6-progress-bar\" class=\"bg-gradient-to-r from-blue-500 to-cyan-400 h-full w-0 transition-all duration-300 rounded-full\"><\/div>\n      <\/div>\n      <span class=\"text-xs font-bold text-cyan-300\"><span id=\"mcq6-answered-count\">0<\/span>\/25<\/span>\n    <\/div>\n  <\/div>\n\n  <!-- Quiz Questions Container -->\n  <div class=\"space-y-8 relative\">\n\n    <!-- Q1 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q1<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          A 62-year-old man with symptomatic heart failure with reduced ejection fraction (HFrEF, LVEF 30%) is currently on optimal medical therapy including sacubitril\/valsartan, metoprolol succinate, and dapagliflozin. His resting heart rate is 84 bpm in normal sinus rhythm. Which additional agent is indicated to further reduce heart failure hospitalizations?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Digoxin provides modest symptom relief and reduces hospitalizations but does not improve overall survival in HFrEF.\">A. Digoxin initiation<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Ivabradine is indicated in patients with symptomatic HFrEF (LVEF &lt;= 35%), in normal sinus rhythm with a resting heart rate &gt;= 70 bpm, who are on maximally tolerated beta-blockers.\">B. Ivabradine<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Amlodipine is a dihydropyridine calcium channel blocker with neutral or negative mortality effects in HFrEF and is not used for outcome reduction.\">C. Amlodipine<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Ranolazine is an anti-anginal agent and does not provide prognostic benefit in HFrEF.\">D. Ranolazine<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q2 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q2<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which of the following echocardiographic findings is pathognomonic for cardiac amyloidosis?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Systolic anterior motion (SAM) of the mitral valve is characteristic of hypertrophic obstructive cardiomyopathy.\">A. Systolic anterior motion of the mitral valve<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"A 'speckled' or 'granular sparkling' appearance of the myocardium on 2D echocardiography, coupled with increased wall thickness and low-voltage ECG, is classic for amyloid infiltration.\">B. Granular sparkling myocardial texture with increased ventricular wall thickness<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Hyperdynamic apical contraction with ballooning is characteristic of Takotsubo cardiomyopathy.\">C. Apical ballooning with basal hyperkinesis<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Localized right ventricular free wall akinesia with epsilon waves points toward ARVC.\">D. Regional right ventricular outflow tract akinesia<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q3 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q3<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          In a patient with suspected infective endocarditis who has a prosthetic heart valve, which imaging modality is currently recommended as a first-line advanced test to detect paravalvular extension and abscess formation when TEE is inconclusive?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Routine coronary angiography does not visualize perivalvular soft tissue abscesses effectively.\">A. Invasive coronary angiography<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Cardiac 18F-FDG PET\/CT and cardiac CT angiography are highly valuable advanced modalities for detecting abnormal metabolic activity and paravalvular complications around prosthetic valves.\">B. 18F-FDG PET\/CT or cardiac computed tomography (CT)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Right heart catheterization measures intracardiac pressures but provides no anatomical imaging of valve tissues.\">C. Right heart catheterization with thermodilution<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Transthoracic echocardiography has low sensitivity for prosthetic valve vegetations and abscesses.\">D. Repeat standard transthoracic echocardiography<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q4 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q4<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which of the following antiarrhythmic drugs is classified as a Vaughan-Williams Class III agent that predominantly blocks potassium channels but also possesses beta-blocking and calcium-channel blocking properties?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Flecainide is a Class IC sodium channel blocker.\">A. Flecainide<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Sotalol is a Class III agent with strong beta-blocking properties, but it does not block calcium channels.\">B. Sotalol<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Amiodarone is a unique broad-spectrum antiarrhythmic possessing Class I, II, III, and IV properties, though primarily categorized as Class III due to potassium channel blockade.\">C. Amiodarone<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Dofetilide is a pure, highly selective Class III rapid delayed rectifier potassium current (IKr) blocker.\">D. Dofetilide<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q5 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q5<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          According to current ACC\/AHA guidelines, what is the class of recommendation for transcatheter aortic valve replacement (TAVR) in patients with severe symptomatic aortic stenosis who are at low surgical risk and aged &gt;= 80 years?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"For patients aged &gt;= 80 years or with a life expectancy &lt; 10 years, TAVR is a Class I recommendation regardless of surgical risk score.\">A. Class I<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Class IIa is not the primary designation for elderly low-risk patients where TAVR is established as a co-equal or preferred option.\">B. Class IIa<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Class IIb indicates weak supportive data, which contradicts modern trial outcomes.\">C. Class IIb<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Class III implies harm or lack of benefit, which is incorrect.\">D. Class III (Harm)<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q6 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q6<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which coronary artery is the most common culprit vessel in anterior wall ST-elevation myocardial infarction (STEMI)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Right coronary artery occlusion typically results in inferior STEMI.\">A. Right Coronary Artery (RCA)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"The left anterior descending (LAD) artery supplies the anterior wall of the left ventricle and interventricular septum.\">B. Left Anterior Descending (LAD) Artery<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Left circumflex artery occlusion typically causes lateral or posterolateral STEMI.\">C. Left Circumflex Artery (LCx)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Isolated obtuse marginal branch occlusion usually causes lateral wall ischemia.\">D. Obtuse Marginal Branch (OM)<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q7 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q7<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary mechanism of action of non-dihydropyridine calcium channel blockers (verapamil and diltiazem)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Direct potassium channel agonism is not their mechanism.\">A. Activation of inward rectifier potassium channels<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Non-dihydropyridine CCBs block L-type voltage-sensitive calcium channels in cardiac and vascular smooth muscle, decreasing myocardial contractility, slowing AV nodal conduction, and causing vasodilation.\">B. Inhibition of L-type calcium channels in the myocardium and AV node<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Inhibition of sodium-potassium ATPase pump is the mechanism of digoxin.\">C. Inhibition of sarcolemmal sodium-potassium ATPase<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Beta-1 adrenergic receptor blockade is the mechanism of beta-blockers.\">D. Competitive antagonism of myocardial beta-1 adrenergic receptors<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q8 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q8<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which genetic syndrome is classically associated with supravalvular aortic stenosis and peripheral pulmonary stenosis?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Marfan syndrome is associated with aortic root dilation and type A aortic dissections.\">A. Marfan Syndrome<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Williams syndrome (microdeletion on chromosome 7q11.23 encompassing the elastin gene) is classically associated with supravalvular aortic stenosis and peripheral pulmonary artery stenoses.\">B. Williams Syndrome<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Down syndrome is associated with endocardial cushion defects (atrioventricular septal defects).\">C. Down Syndrome (Trisomy 21)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Turner syndrome is associated with bicuspid aortic valve and coarctation of the aorta.\">D. Turner Syndrome<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q9 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q9<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary diagnostic hemodynamic feature of pulmonary arterial hypertension (PAH, Group 1 WHO) measured during right heart catheterization?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"PAH is defined by a mean pulmonary arterial pressure &gt; 20 mmHg, pulmonary capillary wedge pressure &lt;= 15 mmHg, and pulmonary vascular resistance &gt; 2 Wood units.\">A. Mean PAP &gt; 20 mmHg with PCWP &lt;= 15 mmHg and PVR &gt; 2 Wood units<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"PCWP &gt; 15 mmHg defines post-capillary pulmonary hypertension secondary to left heart disease.\">B. Mean PAP &gt; 25 mmHg with PCWP &gt; 18 mmHg<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Normal mean PAP is below 20 mmHg.\">C. Normal mean PAP with elevated cardiac index<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Elevated right atrial pressure alone without specific PA pressures is non-diagnostic.\">D. Isolated right atrial pressure &gt; 15 mmHg with normal pulmonary pressures<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q10 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q10<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which anticoagulant is preferred for stroke prevention in a patient with non-valvular atrial fibrillation and end-stage renal disease (CrCl &lt; 15 mL\/min or on hemodialysis)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Rivaroxaban is heavily dependent on renal clearance and lacks safety data in dialysis-dependent ESRD.\">A. Rivaroxaban<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Apixaban and Warfarin are the most widely studied and endorsed oral anticoagulants for stroke prevention in ESRD\/dialysis patients, with apixaban showing favorable bleeding profiles.\">B. Apixaban or Warfarin<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Dabigatran is 80% renally cleared and contraindicated in severe renal failure.\">C. Dabigatran<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Edoxaban efficacy is reduced in patients with high creatinine clearance (creatinine clearance washout phenomenon) and unstudied in dialysis.\">D. Edoxaban<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q11 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q11<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which cardiac biomarker is synthesized primarily in the ventricular myocardium in response to wall stretch and volume overload, serving as a powerful diagnostic and prognostic tool in heart failure?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Troponin is a structural regulatory protein released during myocardial necrosis, not stretch.\">A. Cardiac Troponin I<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"B-type natriuretic peptide (BNP) and NT-proBNP are released from ventricular myocytes in response to increased wall tension and stretch.\">B. B-type Natriuretic Peptide (BNP)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Myoglobin is a rapid non-specific marker of muscle injury.\">C. Myoglobin<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"C-reactive protein is a systemic marker of general inflammation.\">D. C-Reactive Protein (CRP)<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q12 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q12<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary goal of cardiac resynchronization therapy (CRT) in patients with HFrEF, wide QRS complex, and left bundle branch block (LBBB)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"CRT aims to synchronize mechanical contraction, not induce heart block.\">A. Complete ablation of the atrioventricular node<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"CRT restores synchrony between the right and left ventricles (biventricular pacing), reducing mitral regurgitation, improving ejection fraction, and reversing ventricular remodeling.\">B. Restoring electrical and mechanical synchrony between the right and left ventricles<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"CRT does not alter coronary vascular resistance.\">C. Reducing coronary vascular resistance in epicardial vessels<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Uncontrolled tachycardia is not the target of resynchronization.\">D. Maintaining resting heart rate above 100 bpm<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q13 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q13<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which physical exam maneuver increases the murmur of hypertrophic obstructive cardiomyopathy (HOCM)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Squatting increases venous return and preload, enlarging the left ventricular cavity and decreasing the LVOT obstruction and murmur.\">A. Squatting from a standing position<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Valsalva strain decreases venous return (preload) and left ventricular volume, bringing the ventricular septum closer to the anterior mitral leaflet, worsening obstruction and intensifying the HOCM murmur.\">B. Valsalva maneuver or standing up quickly<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Passive leg raise increases preload, which diminishes the HOCM murmur.\">C. Passive leg raise while supine<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Handgrip exercise increases afterload and preload, decreasing the HOCM murmur (unlike aortic stenosis or mitral regurgitation).\">D. Isometric handgrip exercise<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q14 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q14<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary pathology in Takotsubo cardiomyopathy (broken heart syndrome)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Atherosclerotic plaque rupture with epicardial thrombosis causes classic acute myocardial infarction, not Takotsubo.\">A. Acute left main coronary artery thrombosis<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Takotsubo cardiomyopathy is characterized by transient left ventricular apical and mid-ventricular ballooning in the absence of obstructive coronary disease, strongly mediated by catecholamine excess.\">B. Catecholamine-mediated transient apical myocardial stunning without obstructive CAD<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Viral myocarditis produces patchy lymphocytic infiltration and necrosis rather than transient apical ballooning.\">C. Fulminant viral myocarditis with permanent myocardial necrosis<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Primary genetic sarcomeric mutations underlie familial hypertrophic cardiomyopathy.\">D. Sarcomeric gene mutations leading to asymmetric septal hypertrophy<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q15 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q15<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which lipid-lowering agent inhibits cholesterol absorption at the brush border of the small intestine by targeting the NPC1L1 transporter?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Atorvastatin is an HMG-CoA reductase inhibitor.\">A. Atorvastatin<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Ezetimibe selectively inhibits the Niemann-Pick C1-Like 1 (NPC1L1) transporter, reducing intestinal cholesterol absorption.\">B. Ezetimibe<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Evolocumab is a monoclonal antibody targeting circulating PCSK9.\">C. Evolocumab<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Fenofibrate is a PPAR-alpha agonist used primarily for severe hypertriglyceridemia.\">D. Fenofibrate<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q16 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q16<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the classic ECG sign of hyperkalemia in its earliest stages?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Tall, peaked (narrow-based) T waves are the earliest electrocardiographic manifestation of rising extracellular potassium levels.\">A. Tall, peaked, symmetrical T waves<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Prolonged QT interval is characteristic of hypocalcemia or hypokalemia.\">B. Prolonged QT interval with U waves<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"ST elevation in V1-V3 is seen in Brugada syndrome or acute anterior STEMI.\">C. Coved ST-segment elevation in leads V1-V3<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Shortened PR interval with delta waves is characteristic of Wolff-Parkinson-White syndrome.\">D. Shortened PR interval with delta waves<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q17 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q17<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which congenital heart defect is characterized by the classic &#8216;snowman&#8217; (or figure-of-eight) appearance on plain chest radiography?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Tetralogy of Fallot classically produces a 'boot-shaped' heart (coeur en sabot) on chest X-ray.\">A. Tetralogy of Fallot<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Transposition of the great arteries classically shows an 'egg on a string' appearance.\">B. Transposition of the Great Arteries<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Total anomalous pulmonary venous return (TAPVR) above the diaphragm creates a dilated vertical vein and superior vena cava forming the classic 'snowman' or figure-of-eight sign.\">C. Total Anomalous Pulmonary Venous Return (TAPVR)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Truncus arteriosus presents with cardiomegaly and increased pulmonary vascular markings without a snowman silhouette.\">D. Truncus Arteriosus<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q18 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q18<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which of the following interventions has been proven to reduce mortality in patients with ST-elevation myocardial infarction presenting within 12 hours of symptom onset when primary PCI is unavailable within 120 minutes?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Routine high-dose steroid therapy is contraindicated in acute myocardial infarction due to impaired scar healing and rupture risk.\">A. High-dose intravenous methylprednisolone<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Immediate fibrinolytic therapy (if no absolute contraindications exist) combined with antiplatelet therapy is indicated when primary PCI cannot be performed within the 120-minute window.\">B. Timely administration of intravenous fibrinolytic therapy<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Immediate administration of oral calcium channel blockers does not reduce mortality in acute STEMI.\">C. Immediate oral diltiazem loading<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Delayed elective angiography at 2 weeks is inadequate for acute STEMI management.\">D. Delayed elective coronary angiography at 14 days<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q19 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q19<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which hemodynamic profile is characteristic of cardiac tamponade?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Cardiac tamponade features equalization of diastolic pressures across all four chambers (RA, RV diastolic, PA diastolic, and PCWP\/LVEDP) alongside prominent x descent and absent y descent in right atrial pressure.\">B. Equalization of diastolic pressures across all four chambers with blunted y descent<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Steep y descent is characteristic of constrictive pericarditis or restrictive cardiomyopathy, whereas tamponade blunts the y descent due to restricted filling.\">A. Steep y descent with prominent dip-plateau waveform<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Normal right atrial pressure rules out significant tamponade physiology.\">C. Normal right atrial pressure with massive LV hypertrophy<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Isolated left ventricular hypertension without elevated right-sided pressures does not define tamponade.\">D. Isolated left ventricular end-diastolic pressure above 40 mmHg with normal RV pressures<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q20 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q20<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which class of oral antiplatelet medications specifically blocks the protease-activated receptor-1 (PAR-1) on platelets, inhibiting thrombin-induced platelet aggregation?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Thienopyridines block the P2Y12 adenosine diphosphate receptor.\">A. Thienopyridines (e.g., Clopidogrel)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Vorapaxar is a first-in-class oral protease-activated receptor-1 (PAR-1) antagonist that inhibits thrombin-induced platelet activation.\">B. Protease-activated receptor-1 (PAR-1) antagonists (e.g., Vorapaxar)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Glycoprotein IIb\/IIIa inhibitors block fibrinogen binding to the platelet surface integrin receptor.\">C. Glycoprotein IIb\/IIIa receptor antagonists (e.g., Abciximab)<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Phosphodiesterase inhibitors block cAMP degradation to cause vasodilation and mild antiplatelet effects.\">D. Phosphodiesterase-3 inhibitors (e.g., Cilostazol)<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q21 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q21<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which ECG finding is characteristic of Wellens Syndrome (anterior descending coronary stenosis)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Tall peaked T waves are seen in hyperkalemia or hyperacute STEMI.\">A. Tall hyperacute upright T waves in inferior leads<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Wellens syndrome is characterized by deeply inverted or biphasic T waves in leads V2 and V3 (Type A and Type B) in pain-free intervals, indicating critical proximal LAD stenosis.\">B. Deeply inverted or biphasic T waves in leads V2 and V3 during pain-free intervals<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"PR segment elevation in aVR with widespread ST depression suggests left main coronary artery disease.\">C. ST elevation in lead aVR with widespread ST depression<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Right axis deviation with deep S waves in I is characteristic of right ventricular strain.\">D. Right axis deviation with S1Q3T3 pattern<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q22 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q22<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which pharmacological agent is indicated for rhythm control in patients with symptomatic paroxysmal atrial fibrillation who have no structural heart disease or ischemic heart disease?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Flecainide and propafenone (Class IC agents) are first-line oral antiarrhythmic drugs for rhythm control in patients with paroxysmal AF and structurally normal hearts.\">A. Flecainide or Propafenone<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Class IC agents are strictly contraindicated in patients with coronary artery disease or structural heart disease due to increased mortality (CAST trial).\">B. High-dose oral flecainide in patients with recent myocardial infarction<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Dronedarone is contraindicated in permanent AF and severe heart failure.\">C. Dronedarone in permanent heart failure<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Digoxin is a rate control agent and has no efficacy for converting or maintaining sinus rhythm in paroxysmal AF.\">D. Digoxin monotherapy for rhythm conversion<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q23 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q23<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary pathophysiology of pulmonary capillary wedge pressure (PCWP) elevation in heart failure with preserved ejection fraction (HFpEF)?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"HFpEF is characterized by impaired left ventricular relaxation and increased chamber stiffness (diastolic dysfunction), leading to elevated left ventricular end-diastolic pressures and backward transmission into the PCWP.\">A. Left ventricular diastolic dysfunction resulting in increased ventricular filling pressures<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Massive systolic pump failure defines HFrEF, not HFpEF.\">B. Severe systolic myocardial fiber necrosis and low ejection fraction<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Isolated pulmonic valve stenosis elevates RV and PA pressures without affecting PCWP.\">C. Isolated congenital pulmonic valve stenosis<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Primary tricuspid regurgitation affects right atrial and right ventricular hemodynamics.\">D. Massive primary tricuspid valve regurgitation<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q24 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q24<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          Which drug class is established as cornerstone neurohormonal blockade in HFrEF, demonstrating proven reductions in both morbidity and mortality?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"ARNI (or ACE inhibitors\/ARBs), beta-blockers, mineralocorticoid receptor antagonists (MRAs), and SGLT2 inhibitors form the 'fantastic four' foundational guideline-directed medical therapy for HFrEF.\">A. ARNI \/ ACE inhibitors, Beta-blockers, MRAs, and SGLT2 inhibitors<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Loop diuretics provide essential symptom relief of fluid overload but do not alter long-term survival in HFrEF.\">B. High-dose loop diuretics monotherapy<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Dihydropyridine CCBs lack survival benefit and can worsen heart failure.\">C. Dihydropyridine calcium channel blockers<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Alpha-1 blockers increase mortality in heart failure (ALLHAT trial findings).\">D. Selective alpha-1 adrenergic blockers<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n    <!-- Q25 -->\n    <div class=\"quiz-card bg-slate-900\/60 border border-solid border-slate-800 rounded-2xl p-5 md:p-6 shadow-lg transition-all duration-300\" data-answered=\"false\">\n      <div class=\"flex items-start gap-3 mb-4\">\n        <span class=\"bg-blue-950 text-cyan-300 font-extrabold px-3 py-1.5 rounded-lg text-sm border border-solid border-blue-500\/30\">Q25<\/span>\n        <h3 class=\"text-lg md:text-xl font-bold text-slate-100 m-0 leading-snug\">\n          What is the primary mechanism of action of milrinone in acute decompensated heart failure?\n        <\/h3>\n      <\/div>\n      <div class=\"grid grid-cols-1 md:grid-cols-2 gap-3 mb-4\">\n        <button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"true\" data-explanation=\"Milrinone is a phosphodiesterase-3 (PDE-3) inhibitor that increases intracellular cAMP in cardiac myocytes and vascular smooth muscle, producing positive inotropy and systemic\/pulmonary vasodilation (inodilator).\">A. Inhibition of phosphodiesterase-3 leading to increased intracellular cAMP, inotropy, and vasodilation<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Pure alpha-1 agonism causes intense vasoconstriction (e.g., phenylephrine).\">B. Direct stimulation of vascular alpha-1 adrenergic receptors<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Beta-2 selective agonism is used for bronchodilation rather than cardiac inotropy.\">C. Selective stimulation of beta-2 adrenergic receptors<\/button><button type=\"button\" class=\"opt-btn text-left p-4 rounded-xl border-2 border-solid border-slate-800 bg-slate-950 hover:bg-slate-900 transition-all text-sm md:text-base font-semibold text-slate-300 cursor-pointer\" data-correct=\"false\" data-explanation=\"Aldosterone receptor antagonism is the mechanism of spironolactone.\">D. Competitive blockade of renal mineralocorticoid receptors<\/button>\n      <\/div>\n      <div class=\"feedback-box hidden p-4 rounded-xl text-sm md:text-base leading-relaxed\"><\/div>\n    <\/div>\n\n  <\/div>\n<\/div>\n\n<script>\n  let mcq6Correct = 0;\n  let mcq6Answered = 0;\n  const mcq6Total = 25;\n\n  document.querySelectorAll('#mcq6-quiz-wrapper .quiz-card').forEach(card => {\n    const buttons = card.querySelectorAll('.opt-btn');\n    buttons.forEach(btn => {\n      btn.addEventListener('click', function() {\n        if (card.getAttribute('data-answered') === 'true') return;\n        card.setAttribute('data-answered', 'true');\n        mcq6Answered++;\n\n        document.getElementById('mcq6-answered-count').innerText = mcq6Answered;\n        const pct = (mcq6Answered \/ mcq6Total) * 100;\n        document.getElementById('mcq6-progress-bar').style.width = pct + '%';\n\n        buttons.forEach(b => {\n          b.disabled = true;\n          b.classList.remove('hover:bg-slate-900', 'cursor-pointer');\n          b.classList.add('opacity-50', 'cursor-not-allowed');\n        });\n\n        const isCorrect = this.getAttribute('data-correct') === 'true';\n        const explanation = this.getAttribute('data-explanation');\n\n        if (isCorrect) {\n          mcq6Correct++;\n          document.getElementById('mcq6-correct-count').innerText = mcq6Correct;\n          this.classList.remove('opacity-50', 'border-slate-800', 'bg-slate-950');\n          this.classList.add('bg-emerald-950\/80', 'border-emerald-500', 'text-emerald-200', 'opacity-100', 'border-2');\n          this.innerHTML += ' <span class=\"font-bold\">&#10004; CORRECT!<\/span>';\n        } else {\n          this.classList.remove('opacity-50', 'border-slate-800', 'bg-slate-950');\n          this.classList.add('bg-rose-950\/80', 'border-rose-500', 'text-rose-200', 'opacity-100', 'border-2');\n          this.innerHTML += ' <span class=\"font-bold\">&#10006; INCORRECT<\/span>';\n\n          buttons.forEach(b => {\n            if (b.getAttribute('data-correct') === 'true') {\n              b.classList.remove('opacity-50', 'border-slate-800', 'bg-slate-950');\n              b.classList.add('bg-emerald-950\/40', 'border-emerald-500\/55', 'text-emerald-200', 'opacity-100', 'border-2');\n              b.innerHTML += ' <span class=\"font-bold\">&#10004; (Correct)<\/span>';\n            }\n          });\n        }\n\n        const feedback = card.querySelector('.feedback-box');\n        feedback.innerHTML = `\n          <div class=\"font-extrabold uppercase tracking-widest text-xs mb-2 ${isCorrect ? 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His resting heart [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":67944,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","nfd_image_url":"","nfd_onboarding_generated":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-67941","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New Series of Interactive Cardiology MCQs 6 - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/new-series-of-interactive-cardiology-mcqs-6\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Series of Interactive Cardiology MCQs 6 - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"\u2764\ufe0f Advanced Cardiology Series &#8211; Part 6 Interactive Cardiology MCQs #6 Post-Graduate Level Clinical &#038; Hemodynamic Masterclass \ud83c\udfc6 Live Scoreboard 0\/ 25 Correct Progress: 0\/25 Q1 A 62-year-old man with symptomatic heart failure with reduced ejection fraction (HFrEF, LVEF 30%) is currently on optimal medical therapy including sacubitril\/valsartan, metoprolol succinate, and dapagliflozin. 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