{"id":9267,"date":"2012-05-11T08:18:17","date_gmt":"2012-05-11T14:18:17","guid":{"rendered":"http:\/\/www.cardiophile.net\/?p=7881"},"modified":"2012-05-11T08:18:17","modified_gmt":"2012-05-11T14:18:17","slug":"why-are-cpk-and-sgpt-monitored-while-giving-statins","status":"publish","type":"post","link":"https:\/\/johnsonfrancis.org\/professional\/why-are-cpk-and-sgpt-monitored-while-giving-statins\/","title":{"rendered":"Why are CPK and SGPT monitored while giving statins?"},"content":{"rendered":"<h2><span style=\"color: #008000;\">Why are CPK and SGPT monitored while giving statins?<\/span><\/h2>\n<p>Statins are a group of medicines used for lowering cholesterol levels and they have many beneficial effects. Two potential adverse effects of statins are muscle damage and liver injury. Elevation of SGPT indicates liver injury and elevation of CPK suggests muscle damage. The cut off values of importance are SGPT more than three times the upper limit of normal (ULN) and CPK ten times the ULN. Statins can very rarely cause significant liver injury and muscle injury. The latter can very rarely cause myoglobinuria and kidney failure.<\/p>\n<p>CPK monitoring is mostly done only when there are muscle symptoms rather than as routine monitoring<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Statins are a group of medicines used for lowering cholesterol level. Two potential adverse effects of statins are muscle damage and liver injury.<\/p>\n","protected":false},"author":1,"featured_media":35417,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-9267","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-heart-disease-faq"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Why are CPK and SGPT monitored while giving statins? - All About Cardiovascular System and Disorders<\/title>\n<meta name=\"description\" content=\"Statins are a group of medicines used for lowering cholesterol level. Two potential adverse effects of statins are muscle damage and liver injury.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/johnsonfrancis.org\/professional\/why-are-cpk-and-sgpt-monitored-while-giving-statins\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Why are CPK and SGPT monitored while giving statins? - All About Cardiovascular System and Disorders\" \/>\n<meta property=\"og:description\" content=\"Statins are a group of medicines used for lowering cholesterol level. Two potential adverse effects of statins are muscle damage and liver injury.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/johnsonfrancis.org\/professional\/why-are-cpk-and-sgpt-monitored-while-giving-statins\/\" \/>\n<meta property=\"og:site_name\" content=\"All About Cardiovascular System and Disorders\" \/>\n<meta property=\"article:published_time\" content=\"2012-05-11T14:18:17+00:00\" \/>\n<meta name=\"author\" content=\"Johnson Francis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Johnson Francis\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/\"},\"author\":{\"name\":\"Johnson Francis\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"headline\":\"Why are CPK and SGPT monitored while giving statins?\",\"datePublished\":\"2012-05-11T14:18:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/\"},\"wordCount\":121,\"publisher\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#\\\/schema\\\/person\\\/5441d907049b914770f4bd98fb57feec\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"articleSection\":[\"Heart Disease FAQ\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/\",\"url\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/\",\"name\":\"Why are CPK and SGPT monitored while giving statins? - All About Cardiovascular System and Disorders\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/johnsonfrancis.org\\\/professional\\\/why-are-cpk-and-sgpt-monitored-while-giving-statins\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"datePublished\":\"2012-05-11T14:18:17+00:00\",\"description\":\"Statins are a group of medicines used for lowering cholesterol level. 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