Site icon All About Cardiovascular System and Disorders

P2Y12 antagonists

P2Y12 antagonists

P2Y12 antagonists can be classified into three generations depending whether they are reversible or irreversible inhibitors and whether they are competitive or non competitive.

First generation: Irreversible P2Y12 antagonists 

1. Ticlopidine
2. Clopidogrel
3. Prasugrel

Second generation: Reversible, non-competitive P2Y12 antagonists

1. Cangrelor
2. Ticagrelor

Third generation: Reversible, Competitive P2Y12 antagonists

1. Elinogrel

Exit mobile version