Colchicine is a well known drug used in the treatment of acute gouty arthritis, having use in familial Mediterranean fever and acute pericarditis. Two recent studies – COLCOT
Canakinumab is a humanized monoclonal antibody targeting interleukin-1β. Experimental and clinical information had suggested that reducing inflammation even without affecting lipid levels may reduce the risk of cardiovascular
Angiopoietin-like protein 3 (ANGPTL3) is a protein synthesised by liver cells. It inhibits the expression lipoprotein lipase (LPL) gene. That will increase circulating triglycerides. Genetic activation of LPL
Inclisiran is a small interfering RNA (siRNA), which inhibit the production of PCSK9 in the liver. Unlike PCSK9 inhibitors which require monthly or biweekly injections, Inclisiran need be
I was really intrigued when I read in Braunwald’s textbook of Heart Disease that it was William Kouwenhoven, an engineer in Baltimore who described closed chest cardiac massage!
Popular classification of antiarrhythmic agents into Class I to IV was proposed by: A. Willis Hurst B. Eugene Braunwald C. Vaughan-Williams D. André Frédéric Cournand Correct answer: C.
Surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) are both effective methods for treating adults with severe symptomatic aortic stenosis. Early mortality and stroke are
Alfieri stitch is used in the treatment of: A. Mitral stenosis B. Mitral regurgitation C. Aortic stenosis D. Pulmonary stenosis Correct answer: B. Mitral regurgitation Alfieri stitch is
Percutaneous balloon mitral valvuloplasty was introduced by: A. Gruentzig B. Cournand C. Inoue D. Braunwald Correct answer: C. Inoue Inoue and team described percutaneous balloon mitral valvuloplasty in
