Clonal hematopoiesis of indeterminate potential (CHIP) is due to somatic mutations which cause expansion of hematopoietic stem cells. This is in the absence of overt hematologic malignancy. CHIP
HeartMate 3 is a fully magnetically levitated centrifugal flow intrathoracic left ventricular assist device. It has wider blood flow pathways compared to its predecessor Heartmate II. It has
Colchicine is a well known drug used in the treatment of acute gouty arthritis, having use in familial Mediterranean fever and acute pericarditis. Two recent studies – COLCOT
Canakinumab is a humanized monoclonal antibody targeting interleukin-1β. Experimental and clinical information had suggested that reducing inflammation even without affecting lipid levels may reduce the risk of cardiovascular
Angiopoietin-like protein 3 (ANGPTL3) is a protein synthesised by liver cells. It inhibits the expression lipoprotein lipase (LPL) gene. That will increase circulating triglycerides. Genetic activation of LPL
Inclisiran is a small interfering RNA (siRNA), which inhibit the production of PCSK9 in the liver. Unlike PCSK9 inhibitors which require monthly or biweekly injections, Inclisiran need be
I was really intrigued when I read in Braunwald’s textbook of Heart Disease that it was William Kouwenhoven, an engineer in Baltimore who described closed chest cardiac massage!
Popular classification of antiarrhythmic agents into Class I to IV was proposed by: A. Willis Hurst B. Eugene Braunwald C. Vaughan-Williams D. André Frédéric Cournand Correct answer: C.
Surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) are both effective methods for treating adults with severe symptomatic aortic stenosis. Early mortality and stroke are
