Cardiology MCQ – Anti-Ro/SSA – Answer

Cardiology MCQ – Anti-Ro/SSA – Answer

Maternal Anti-Ro/SSA antibodies are associated with fetal:

Correct answer: 4. All of the above

Fetal echocardiographic features of anti-Ro/SSA antibody–mediated cardiac disease includes dilated cardiomyopathy, pericardial effusion, endocardial fibroelastosis, complete heart block and atrioventricular valve regurgitation [1]. But the one familiar to most people is complete heart block in the infant of mother with systemic lupus erythematosus or other maternal connective tissue disease [2].

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  1. Cuneo BF, Sonesson SE, Levasseur S, Moon-Grady AJ, Krishnan A, Donofrio MT, Raboisson MJ, Hornberger LK, Van Eerden P, Sinkovskaya E, Abuhamad A, Arya B, Szwast A, Gardiner H, Jacobs K, Freire G, Howley L, Lam A, Kaizer AM, Benson DW, Jaeggi E. Home Monitoring for Fetal Heart Rhythm During Anti-Ro Pregnancies. J Am Coll Cardiol. 2018 Oct 16;72(16):1940-1951.
  2. Jayaprasad N, Johnson F, Venugopal K. Congenital complete heart block and maternal connective tissue disease. Int J Cardiol. 2006 Sep 20;112(2):153-8.