Vernakalant hydrochloride is a novel anti arrhythmic agent which is atrial selective, blocking the early activating potassium channel and frequency dependent sodium channel.
Statins reduce progression of atherosclerotic AS. Study suggests statins may have a role in reducing the progression of rheumatic mitral valve disease also.
Sleep apnea and cardiovascular disease: sleep apnea can cause hypertension, bradyarrhythmias, AF, pulmonary hypertension and precipitate nocturnal angina.
Management of primary pulmonary hypertension: latest addition to the therapeutic armamentarium are oral endothelin antagonists bosentan and ambrisentan.