Antiarrhythmics after ablation of AF (5A Study) Antiarrhythmic drugs after ablation of atrial fibrillation (5A Study) was published in Circulation in 2009 [1]. One hundred and ten patients after
SCD-HeFT 2005 The Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) trial was published in NEJM in 2005 [1]. SCD-HeFT randomized 2521 patients into three groups. They were in New
Vernakalant – class IIIa Vernakalant is a class IIIa antiarrhythmic agent as per the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. The class effect is voltage dependent K+
Adenosine – Class IIe Adenosine is a class IIe antiarrhythmic agent as per the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. Autonomic inhibitors and activators constitute new class
Ibutilide – class IIIa Ibutilide is a class IIIa antiarrhythmic agent as per the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. The class effect is voltage dependent K+
Sotalol – class IIIa Sotalol is a class IIIa antiarrhythmic agent as per the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. The class effect is voltage dependent K+
Amiodarone – class IIIa Amiodarone is designated as class IIIa antiarrhythmic agent in the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. This is the group of voltage dependent
Ranolazine – Class Id Ranolazine, originally introduced as an antianginal agent for the treatment of chronic stable angina, is now being recognized as an antiarrhythmic agent as well.
Propafenone Propafenone is a Class Ic drug with targets INa, IKr and IKur currents as well as beta receptors and alpha receptors [1,2]. It can cause PR interval prolongation,
Flecainide Flecainide is a class Ic drug which reduces the peak INa (sodium current), (dV/dt)max, IKr (rapid component of the delayed rectifier potassium current), IKur (ultrarapid component of the delayed rectifier