Category: Cardiology

ATP and ADP bind to platelet P2 receptors. The platelet receptors for ADP are P2Y1 and P2Y12 while those from ATP is P2X1.

S5 lead is used for enhancing atrial activity.

Coronary bifurcations with an angle of less than 70 degrees are known as Y-shaped bifurcation and those with more than 70 degrees T-shaped bifurcation.

Recent advances in communication devices and electrocardiographic technology have enabled real time loop recorder with telemonitoring.

The presence of hypertension in AS makes it (left ventricle) a double loaded LV with valvular obstruction and vascular resistance presenting dual loads.

RE-LY trial: In patients with AF, dabigatran given at a dose of 110 mg was associated with stroke rates similar to warfarin, but with less major bleeding.

Tripling the dose was found to be useful in those with heterozygous mutation producing clopidogrel resistance, while it was not useful in homozygous cases.

Ticagrelor is an antiplatelet agent belonging to a new class known as cyclopentyl triazolo-pyrimidines (CPTP) acting as a reversible allosteric antagonist.

AF ablation on therapeutic anticoagulation is being studied more often with an end point of less thromboembolism and acceptable bleeding risk.

Programmed stimulator for electrophysiology (EP) study is used to give pacing at particular rates and protocols as needed.