Chest compression rate affect ROSC, not survival to hospital discharge

Chest compression ROSC, not survival to hospital discharge

Chest compression rate affect ROSC: Ahamed H Idris, Danielle Guffey, Tom P Aufderheide, Siobhan Brown, Laurie J Morrison, Patrick Nichols, Judy Powell, Mohamud Daya, Blair L Bigham, Dianne L Atkins, Robert Berg, Dan Davis, Ian Stiell, George Sopko and Graham Nichol of the Resuscitation Outcomes Consortium (ROC) Investigators [1] have found that chest compression rates during cardiopulmonary resuscitation (CPR) affect return of spontaneous circulation, but not survival to hospital discharge. In a study involving 3098 subjects with out of hospital cardiac arrests, return of spontaneous circulation peaked at a chest compression rate of around 125 per minute and declined further. This is higher than the standard CPR recommendation of 100 per minute chest compressions. Earlier animal and human studies have reported that blood flow is greatest with chest compression rates around 120 per minute.

Though the return of spontaneous circulation was higher at higher rates of chest compression, this did not translate into higher rates of survival up to hospital discharge, which is a more desirable outcome.

Mean age of the study group was 67 ± 16 years and the mean compression rate was 112 ± 19 per minute. Only 8.6% survived to hospital discharge.

Reference

1. Ahamed H Idris, Danielle Guffey, Tom P Aufderheide, Siobhan Brown, Laurie J Morrison, Patrick Nichols, Judy Powell, Mohamud Daya, Blair L Bigham, Dianne L Atkins, Robert Berg, Dan Davis, Ian Stiell, George Sopko, Graham Nichol, Resuscitation Outcomes Consortium (ROC) Investigators. Relationship Between Chest Compression Rates and Outcomes From Cardiac Arrest. Circulation. 2012 Jun 19;125(24):3004-12.