Which of the following is not a determinant of left ventricular preload? – Correct Answer: d) Aortic pressure
Aortic pressure determines the left ventricular afterload.
Left atrial pressure is the left ventricular filling pressure. Increase in preload enhances function in normal heart. In a failing heart, initially increasing preload enhances function, but in advanced heart failure, overstretching of the myocardium is counterproductive. Decreasing afterload helps in heart failure by increasing the ventricular performance.