Drugs approved for treatment of normotensive patients with pulmonary embolism

Drugs approved for treatment of normotensive patients with pulmonary embolism:

  1. Heparin
  2. Fondaparinux
  3. Rivaroxaban
  4. Apixaban
  5. Dabigatran
  6. Edoxaban

Thrombolytic therapy is reserved for rescue in case of decompensation due to right ventricular failure or recurrence of pulmonary embolism in these stable patients.

Dabigatran is a direct thrombin inhibitor while rivaroxaban, apixaban and edoxaban are oral factor Xa inhibitors. Fondaparinux is a parenteral factor Xa inhibitor.

 

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