GI bleed with Continuous flow LVAD – Mechanisms Prof. Dr. Johnson Francis | April 13, 2019 | Cardiac Surgery | 1 Comment GI bleed with Continuous flow LVAD – Mechanisms Gastrointestinal bleeds can occur in 15-40% of patients on continuous flow left ventricular assist devices (LVAD) for end stage heart failure. Proposed mechanisms for gastrointestinal bleeds with continuous flow LVAD includes: Acquired von Willebrand disease Impaired platelet aggregation Enhanced angiogenesis causing arteriovenous malformations (AVM) Intensity of anticoagulation AVMs may contribute to about half of the GI bleed with continuous flow LVADS. Hypoperfusion of gastrointestinal mucosa leads to angiogenesis and the new friable vessels are prone for bleeding . Reference Guha A, Eshelbrenner CL, Richards DM, Monsour HP Jr. Gastrointestinal bleeding after continuous-flow left ventricular device implantation: review of pathophysiology and management. Methodist Debakey Cardiovasc J. 2015 Jan-Mar;11(1):24-7. Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related Posts Skeletonized internal mammary graft vs pedicled graft No Comments | Sep 17, 2018 Pulmonary artery banding No Comments | Aug 2, 2014 Management of prosthetic valve thrombosis No Comments | Sep 16, 2008 Robotic repair of mitral valve No Comments | Nov 24, 2015 One Comment Rahul April 13, 2019 Reply Enhanced angiogenesis forming av fistula Add a Comment Cancel reply Your email address will not be published. Required fields are marked *Comment:*Name:* Email Address:* Website: Save my name, email, and website in this browser for the next time I comment. Notify me of follow-up comments by email. Notify me of new posts by email.