GI bleed with Continuous flow LVAD – Mechanisms Prof. Dr. Johnson Francis | April 13, 2019 | Cardiac Surgery | 1 Comment Last Updated on April 13, 2019GI bleed with Continuous flow LVAD – Mechanisms Gastrointestinal bleeds can occur in 15-40% of patients on continuous flow left ventricular assist devices (LVAD) for end stage heart failure. Proposed mechanisms for gastrointestinal bleeds with continuous flow LVAD includes: Acquired von Willebrand disease Impaired platelet aggregation Enhanced angiogenesis causing arteriovenous malformations (AVM) Intensity of anticoagulation AVMs may contribute to about half of the GI bleed with continuous flow LVADS. Hypoperfusion of gastrointestinal mucosa leads to angiogenesis and the new friable vessels are prone for bleeding . Reference Guha A, Eshelbrenner CL, Richards DM, Monsour HP Jr. Gastrointestinal bleeding after continuous-flow left ventricular device implantation: review of pathophysiology and management. Methodist Debakey Cardiovasc J. 2015 Jan-Mar;11(1):24-7. Related Posts Reverse Lutembacher syndrome No Comments | Apr 22, 2012 Unfavourable results with multiple distal targets for SVG No Comments | Jul 22, 2011 Cox maze procedure I, II, III and IV for atrial fibrillation No Comments | Sep 22, 2018 How will you assess the success of repair of mitral valve repair per-operatively? No Comments | Mar 27, 2019 One Comment Rahul April 13, 2019 Enhanced angiogenesis forming av fistula Add a Comment Cancel replyYour email address will not be published. Required fields are marked *Comment:*Name:* Email Address:* Website: Save my name, email, and website in this browser for the next time I comment.