Heyde’s syndrome – MCQ – Answer

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Heyde’s syndrome – MCQ – Answer

Which of the following is not part of Heyde’s syndrome? Correct answer: d) Mitral regurgitation

Large multimers of von Willebrand factor are damaged due to shear stress when they pass through the stenotic aortic valve at high velocity. Type 2 acquired von Willebrand’s disease occurs as a result of this [1]. Intestinal angiodysplasias which are often asymptomatic, start bleeding when there is a deficiency of large multimers of von Willebrand factor, which is essential for hemostasis.


  1. Pate GE, Chandavimol M, Naiman SC, Webb JG. Heyde’s syndrome: a review. J Heart Valve Dis. 2004 Sep;13(5):701-12.

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