New Series of Interactive Cardiology MCQs 11
❤️ Advanced Cardiology Series – Part 11
Interactive Cardiology MCQs #11
Post-Graduate Level Clinical & Hemodynamic Masterclass
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Q1
A 68-year-old man with symptomatic heart failure with reduced ejection fraction (LVEF 28%) and left bundle branch block (QRS duration 160 ms) undergoes successful cardiac resynchronization therapy (CRT-D) implantation. Which echocardiographic parameter assessed post-implant best reflects acute correction of mechanical dyssynchrony?
Q2
Which of the following histologic findings is considered the diagnostic hallmark of cardiac sarcoidosis on endomyocardial biopsy?
Q3
In a patient with severe primary mitral regurgitation who is asymptomatic and has normal left ventricular function (LVEF 65%, LVESD 38 mm), what is the guideline-directed indication for surgical mitral valve repair?
Q4
Which cellular mechanism accounts for early afterdepolarizations (EADs) that can trigger torsades de pointes in congenital long QT syndrome?
Q5
Which scoring system is validated for assessing bleeding risk in patients with atrial fibrillation initiated on oral anticoagulation to identify and modify reversible bleeding risk factors?
Q6
In a patient with acute ST-elevation myocardial infarction (STEMI) presenting with cardiogenic shock, what is the primary indication for placement of a temporary mechanical circulatory support device such as an Impella microaxial pump?
Q7
Which anatomical structure forms the boundaries of the Triangle of Koch, a crucial landmark during electrophysiological ablation of the AV node or slow pathway in AVNRT?
Q8
Which of the following pharmacologic therapies has demonstrated definitive mortality benefit and reduction in heart failure hospitalizations in patients with heart failure with mildly reduced ejection fraction (HFmrEF, LVEF 41-49%)?
Q9
Which physical examination sign involves an inspiratory increase in jugular venous pressure (instead of the normal inspiratory decline)?
Q10
Which imaging technique utilizes myocardial flow reserve (MFR) quantification via PET or stress cardiac MRI to detect microvascular angina and epicardial multivessel coronary disease when standard obstructive angiography is normal?
Q11
Which cardiac condition is classically associated with the insertion of a pacing lead across the tricuspid valve resulting in severe secondary tricuspid regurgitation?
Q12
Which pharmacologic reversal agent is specifically approved for the rapid reversal of dabigatran anticoagulant effects in life-threatening bleeding or urgent surgery?
Q13
What is the primary hemodynamic consequence of an unrestrictive ventricular septal defect (VSD) with a large left-to-right shunt left untreated into adulthood?
Q14
Which type of aortic dissection according to the Stanford classification involves the ascending aorta regardless of the site of the primary intimal tear?
Q15
Which of the following parameters measured during invasive coronary angiography defines a functionally significant coronary stenosis amenable to revascularization in the absence of ischemic symptoms?
Q16
Which cardiac rhythm disturbance is characterized by an irregular-irregular rhythm with at least three distinct P-wave morphologies in a single ECG lead, commonly associated with severe pulmonary disease?
Q17
Which medical therapy is indicated for primary prevention of sudden cardiac death in an adult patient with genetic Long QT Syndrome Type 1 (LQTS1) presenting with recurrent syncopal episodes despite optimal beta-blocker therapy?
Q18
Which echocardiographic measurement is best utilized to assess right ventricular systolic function independently of geometry in patients with pulmonary hypertension?
Q19
Which pathological feature differentiates rheumatic mitral stenosis from degenerative calcific mitral annular stenosis?
Q20
Which pharmacological class of antianginal medications acts primarily by inhibiting the late sodium current (INa) in cardiomyocytes, reducing intracellular sodium and calcium overload without altering heart rate or blood pressure?
Q21
Which genetic mutation and inheritance pattern is classically linked to Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)?
Q22
Which diagnostic modality is considered the gold standard for confirming anomalous left coronary artery from the pulmonary artery (ALCAPA) syndrome in infants and adults?
Q23
Which hemodynamic parameter differentiates vasodilatory septic shock from cardiogenic shock in a patient presenting with multi-organ hypoperfusion?
Q24
Which pharmacological class of pulmonary arterial hypertension (PAH) therapy acts as a prostacyclin receptor agonist promoting pulmonary vasodilation and inhibition of platelet aggregation?
Q25
What is the primary mechanism of action of tafamidis in the management of transthyretin (TTR) cardiac amyloidosis?
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About The Author
Johnson Francis
Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal