New Series of Interactive Cardiology MCQs 6
❤️ Advanced Cardiology Series – Part 6
Interactive Cardiology MCQs #6
Post-Graduate Level Clinical & Hemodynamic Masterclass
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Q1
A 62-year-old man with symptomatic heart failure with reduced ejection fraction (HFrEF, LVEF 30%) is currently on optimal medical therapy including sacubitril/valsartan, metoprolol succinate, and dapagliflozin. His resting heart rate is 84 bpm in normal sinus rhythm. Which additional agent is indicated to further reduce heart failure hospitalizations?
Q2
Which of the following echocardiographic findings is pathognomonic for cardiac amyloidosis?
Q3
In a patient with suspected infective endocarditis who has a prosthetic heart valve, which imaging modality is currently recommended as a first-line advanced test to detect paravalvular extension and abscess formation when TEE is inconclusive?
Q4
Which of the following antiarrhythmic drugs is classified as a Vaughan-Williams Class III agent that predominantly blocks potassium channels but also possesses beta-blocking and calcium-channel blocking properties?
Q5
According to current ACC/AHA guidelines, what is the class of recommendation for transcatheter aortic valve replacement (TAVR) in patients with severe symptomatic aortic stenosis who are at low surgical risk and aged >= 80 years?
Q6
Which coronary artery is the most common culprit vessel in anterior wall ST-elevation myocardial infarction (STEMI)?
Q7
What is the primary mechanism of action of non-dihydropyridine calcium channel blockers (verapamil and diltiazem)?
Q8
Which genetic syndrome is classically associated with supravalvular aortic stenosis and peripheral pulmonary stenosis?
Q9
What is the primary diagnostic hemodynamic feature of pulmonary arterial hypertension (PAH, Group 1 WHO) measured during right heart catheterization?
Q10
Which anticoagulant is preferred for stroke prevention in a patient with non-valvular atrial fibrillation and end-stage renal disease (CrCl < 15 mL/min or on hemodialysis)?
Q11
Which cardiac biomarker is synthesized primarily in the ventricular myocardium in response to wall stretch and volume overload, serving as a powerful diagnostic and prognostic tool in heart failure?
Q12
What is the primary goal of cardiac resynchronization therapy (CRT) in patients with HFrEF, wide QRS complex, and left bundle branch block (LBBB)?
Q13
Which physical exam maneuver increases the murmur of hypertrophic obstructive cardiomyopathy (HOCM)?
Q14
What is the primary pathology in Takotsubo cardiomyopathy (broken heart syndrome)?
Q15
Which lipid-lowering agent inhibits cholesterol absorption at the brush border of the small intestine by targeting the NPC1L1 transporter?
Q16
What is the classic ECG sign of hyperkalemia in its earliest stages?
Q17
Which congenital heart defect is characterized by the classic ‘snowman’ (or figure-of-eight) appearance on plain chest radiography?
Q18
Which of the following interventions has been proven to reduce mortality in patients with ST-elevation myocardial infarction presenting within 12 hours of symptom onset when primary PCI is unavailable within 120 minutes?
Q19
Which hemodynamic profile is characteristic of cardiac tamponade?
Q20
Which class of oral antiplatelet medications specifically blocks the protease-activated receptor-1 (PAR-1) on platelets, inhibiting thrombin-induced platelet aggregation?
Q21
Which ECG finding is characteristic of Wellens Syndrome (anterior descending coronary stenosis)?
Q22
Which pharmacological agent is indicated for rhythm control in patients with symptomatic paroxysmal atrial fibrillation who have no structural heart disease or ischemic heart disease?
Q23
What is the primary pathophysiology of pulmonary capillary wedge pressure (PCWP) elevation in heart failure with preserved ejection fraction (HFpEF)?
Q24
Which drug class is established as cornerstone neurohormonal blockade in HFrEF, demonstrating proven reductions in both morbidity and mortality?
Q25
What is the primary mechanism of action of milrinone in acute decompensated heart failure?
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About The Author
Johnson Francis
Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal