New Series of Interactive Cardiology MCQs 8
Advanced Clinical Series
Cardiology MCQs: Part 8
Master-level assessment spanning complex hemodynamics, electrophysiology, structural interventions, and landmark clinical trials.
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1. In the WHO classification of Pulmonary Hypertension (PH), Chronic Thromboembolic Pulmonary Hypertension (CTEPH) belongs to which group?
2. What is the specific, FDA-approved reversal agent for the direct thrombin inhibitor Dabigatran?
3. Which combination of electrocardiographic findings is the classic triad of Wolff-Parkinson-White (WPW) syndrome pattern?
4. In the United States, what is historically the most common structural cause of sudden cardiac death in young competitive athletes?
5. Kussmaul sign is defined as a paradoxical rise (or failure to fall) of the Jugular Venous Pressure (JVP) during inspiration. It is classically associated with which condition?
6. What is the normal anatomical orifice area of the adult mitral valve?
7. Cilostazol is frequently used to treat claudication in peripheral artery disease (PAD). What is its primary pharmacological mechanism?
8. According to ACC/AHA guidelines, adults aged 40-75 years with diabetes mellitus (without established atherosclerotic cardiovascular disease) should be prescribed:
9. The landmark PARTNER 3 and Evolut Low Risk trials definitively expanded the indication for Transcatheter Aortic Valve Replacement (TAVR) to which patient population?
10. Under the Modified Duke Criteria for infective endocarditis, which of the following is considered a MAJOR criterion?
11. Guideline-Directed Medical Therapy (GDMT) for HFrEF is built upon ‘four pillars’ of medications proven to reduce mortality. Which of the following correctly identifies these four classes?
12. Upon palpation of the carotid artery, a ‘pulsus parvus et tardus’ (a weak and delayed pulse) is the classic physical examination finding for which valvular lesion?
13. Dressler syndrome is a post-myocardial infarction pericarditis that typically presents weeks to months after the event. What is the first-line pharmacologic treatment?
14. SGLT2 inhibitors (like Empagliflozin and Dapagliflozin) have shown dramatic benefits in heart failure. By what mechanism do they function in the kidney?
15. A patient with suspected Prinzmetal (variant) angina experiences episodes of resting chest pain with transient ST-segment elevation. Which class of medication should generally be AVOIDED as it may exacerbate symptoms?
16. The ‘Salvador Dali mustache’ sign on an electrocardiogram is a classic descriptor for which of the following?
17. During a coronary angiogram, a Fractional Flow Reserve (FFR) measurement is taken across an intermediate lesion. Below what threshold value is the lesion considered hemodynamically significant, thereby justifying revascularization?
18. A patient presents to the ER with tearing chest pain. CT Angiography confirms a Stanford Type A aortic dissection. What is the immediate, definitive management strategy?
19. Brugada syndrome is a genetic channelopathy carrying a high risk of sudden cardiac death. It is most commonly associated with a loss-of-function mutation in which gene?
20. A 25-year-old asymptomatic female is found to have a wide, fixed split S2 on cardiac auscultation. This finding is the hallmark of which congenital heart defect?
21. For a patient who receives a Drug-Eluting Stent (DES) during a percutaneous intervention for an Acute Coronary Syndrome (ACS), what is the standard guideline-recommended minimum duration of Dual Antiplatelet Therapy (DAPT)?
22. Which of the following is typically the earliest electrocardiographic manifestation of hyperkalemia?
23. Amiodarone is a highly effective Class III antiarrhythmic, but it has significant systemic toxicities. Patients on chronic therapy require regular monitoring of which three organ systems?
24. During transthoracic echocardiography, which specific finding is the most sensitive indicator of early hemodynamic compromise in a patient with a pericardial effusion?
25. In the evaluation of stable ischemic heart disease, at what percentage of angiographic stenosis is the Left Main Coronary Artery (LMCA) generally considered hemodynamically significant, warranting revascularization?
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About The Author
Johnson Francis
Former Professor of Cardiology, Calicut Govt. Medical Kozhikode, Kerala, India. Editor-in-Chief, BMH Medical Journal