Predisposition to statin adverse effects

Predisposition to statin adverse effects

Some situations likely to predispose to statin adverse effects are impaired renal or hepatic function, history of previous statin intolerance or muscle disorders and unexplained elevation of SGPT. In addition to these, age above 75 years, Asian ancestry and previous hemorrhagic stroke are potential conditions to considered while considering high intensity statin therapy with regard to predisposition for adverse effects. Concomitant usage of drugs likely to affect statin metabolism should also be considered.