Prodrug among DOAC/NOACs – Cardiology MCQ – Answer

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Prodrug among DOAC/NOACs – Cardiology MCQ – Answer

Which of the following DOAC/NOAC is a prodrug? – Correct answer: a) Dabigatran

Only dabigatran etexilate is a prodrug among the DOAC/NOACs. It is transformed to active form by esterases which are ubiquitous [1].

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Reference

  1. Qamar A, Vaduganathan M, Greenberger NJ, Giugliano RP. Oral Anticoagulation in Patients With Liver Disease. J Am Coll Cardiol. 2018 May 15;71(19):2162-2175.