Stuck on plaque in carcinoid heart disease and anorexigen associated valvular heart disease
“Stuck on plaque” is the description given to the lesions on the tricuspid valve in carcinoid heart disease and anorexigen associated valvular heart disease. The lesions appear “stuck on” the leaflets without inflammation or damage to the underlying valve structure [1, 2].
An article in NEJM (free full text) gives the image of a stuck on plaque on an excised mitral valve in fenfluramine associated valvular heart disease . Histopathological section showed that the valve architecture was preserved. The plaque encased the chordae tendinae.
A large surgical pathology series in Mayo Clinic Proceedings on 139 valves from 75 patients over two decades also describes the lesions in carcinoid heart disease .