Starling’s law of the heart

Starling’s law of the heart

It is the volume of the heart which determines the force of contraction. Increase in muscle fibre length increases the force of contraction upto a certain level. Beyond this level, further increase in the volume of the heart produces deterioration of cardiac output. 2.2 microns is the critical sarcomere length at which there is optimal force of contraction, due to good overlap of actin and myosin filaments.