Mitral regurgitation is leakage of the valve between the left atrium and left ventricle so that part of left ventricular blood flows back into left atrium.
Aortic Regurgitation denotes leakage of the valve between left ventricle and the aorta, so that blood flows back into the left ventricle when it relaxes.
Rheumatic fever is an immune mediated disease involving the joints, heart, skin and brain. Commonest manifestation is pain and swelling of multiple joints.
Genetic factors responsible for clopidogrel resistance include polymorphisms of CYP (Cytochrome P), GP Ia (Glycoprotein Ia), P2Y12 and Glycoprotein IIIa.