Cardiology MCQ – Least progression of valvular lesion – Answer

Cardiology MCQ – Least progression of valvular lesion – Answer

Which of these three lesions is least likely to progressive and have a favourable clinical course among aortic stenosis, mitral regurgitation and aortic regurgitation?

Correct Answer: 1. Aortic regurgitation

Asymptomatic severe aortic stenosis and mitral regurgitation has poor long term outcome with overall mortality near to 10% per year, while that of asymptomatic severe aortic regurgitation is almost similar to that of age/sex matched population. 1998 AHA guidelines mentioned annual sudden death risk of only 0.2%, progression to asymptomatic left ventricular dysfunction of less than 1.3% and chance of becoming symptomatic of less than 4.3% per year.

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  1. Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O’Gara PT, O’Rourke RA, Rahimtoola SH, Ritchie JL, Cheitlin MD, Eagle KA, Gardner TJ, Garson A Jr, Gibbons RJ, Russell RO, Ryan TJ, Smith SC Jr. Guidelines for the management of patients with valvular heart disease: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease). Circulation. 1998 Nov 3;98(18):1949-84.