Category: General Cardiology

CURRENT OASIS 7 trial found that double dose clopidogrel was associated with significant reduction in stent thrombosis in those who underwent PCI.

Isolated left ventricular cardiac tamponade can occur postoperatively due to loculated collections posterior to the left ventricle.

Allopurinol added to optimal medications shown to increase the median exercise time to ST segment depression and the total exercise time.

Connexin 40 (Cx40) is a tissue-specific gap junction protein. Gap junctions are important in providing cell to cell coupling for propagation of impulses.

P2Y12 antagonists can be classified into three generations depending whether they are reversible or irreversible inhibitors.

Cardiac involvement in Costello syndrome: hypertrophic cardiomyopathy, valvular pulmonary stenosis, atrial arrhythmias (chaotic atrial rhythm/ MAT or EAT).

Hallmark of cardiac amyloidosis is thickening of ventricular walls seen on echocardiography without corresponding higher voltages on electrocardiography.

Clopidogrel resistance: poor metabolizers do not effectively convert it into active form because of low CYP2C19 activity causing a reduced effectiveness.

Familial hypercholesterolemia is an autosomal dominant disorder caused by mutations in the gene encoding the receptor for low density lipoprotein (LDL).

Fondaparinux is a synthetic polysaccharide which is an indirect, selective factor Xa inhibitor.