High altitude pulmonary edema is characterized by pulmonary vasoconstriction in response to reduced oxygen concentration in inhaled air at high altitude.
Cor pulmonale is heart disease secondary to lung disease which causes pulmonary hypertension. It is associated with RVH, leading to right heart failure.
Sitaxentan, ambrisentan and atrasentan are selective endothelin A receptor antagonists. Bosentan and Tezosentan are non selective endothelin inhibitors.
Cardiovascular risks of obesity: Premature atherosclerosis, risk of myocardial infarction, heart failure, decreased survival, due to cardiovascular deaths.