Category: General Cardiology

Clopidogrel resistance: poor metabolizers do not effectively convert it into active form because of low CYP2C19 activity causing a reduced effectiveness.

Familial hypercholesterolemia is an autosomal dominant disorder caused by mutations in the gene encoding the receptor for low density lipoprotein (LDL).

Fondaparinux is a synthetic polysaccharide which is an indirect, selective factor Xa inhibitor.

Omecamtiv mecarbil is a cardiac myosin activator being evaluated in the treatment of heart failure.

Ambulatory BP monitoring and home monitoring are two methods which have been developed to assess the ‘true’ blood pressure in an ideal setting.

Newer antithrombotics in atrial fibrillation: DTI -dabigatran, direct factor Xa inhibitors - rivaroxaban, apixaban, edoxaban; vitamin K analogue tecarfarin.

Study found that degeneration of bioprosthetic valves is faster in patients with type 2 diabetes mellitus.

Flash pulmonary edema in renal artery stenosis has been called Pickering Syndrome

Allopurinol infusion acutely improves the concentrations of ATP in the myocardium of the failing human heart.

Platelet reactivity can be measured in P2Y12 reaction units (PRU) and can be used to assess on-treatment platelet reactivity (OTR) after PCI.