Patent foramen ovale is a valvular opening in the region of fossa ovalis of interatrial septum, remains closed due to higher pressure on left atrial side.
Though life threatening cardiac arrhythmias are the most important adverse effects seen with digitoxicity, the most common ones are anorexia and nausea.
Myocardial oxygen consumption is the oxygen consumed by heart muscle and the determinants are intramyocardial wall tension, contractility and heart rate.
6 minute walk test is a simple test to estimate the functional capacity in patients who cannot perform a conventional exercise test like treadmill test.