Chatterjee phenomenon

Chatterjee phenomenon

Post pacing T wave inversion has been called Chatterjee phenomenon. In the original article by Kanu Chatterjee and associates [Electrocardiographic changes subsequent to artificial ventricular depolarization. Br Heart J. 1969 31:770-9] they found significant ST depression and T wave inversion persisting after discontinuation of pacing. They noted that the mere presence of the lead in the ventricle or atrial pacing did not produce these changes. They also excluded a recent Stokes Adam attack as the cause of the ST-T changes in their cases. Only depolarization of the ventricles from an abnormal site was deemed to be the cause of these changes.

Cardiac memory has been postulated as a mechanism of these changes by other authors as well [Gautschi O  et al. Cardiac memory mimicking myocardial ischaemia.  J R Soc Med. 2003; 96: 131–132].  Similar changes have also been reported after intermittent left bundle branch block, intermittent preexcitation and episodes of tachycardia (post tachycardia syndrome).

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