Neoatherosclerosis in bioresorbable vascular scaffold

Neoatherosclerosis in bioresorbable vascular scaffold

Neoatherosclerosis in bioresorbable vascular scaffold:  Concerns about the long term utility of bioresorbable vascular scaffold (BVS) in different aspects have been raised. Moriyama N and colleagues looked into the possibility of neoatherosclerosis after implantation BVS implantation [1]. They study group was part of the ABSORB EXTEND (ABSORB EXTEND Clinical Investigation) trial and underwent optical coherence tomography (OCT) at baseline after the index procedure and then at 1 year and 5 years post procedure. One fourth of their patients had diabetes mellitus and nearly half the patients had type B2/C lesions on the baseline angiogram. Significant difference in the prevalence of lipid laden neointima, calcification, neovascularization and thin-cap atheroma were found at five years. At the same time, no significant difference was noted in the plaque prevalence in out-scaffold segments. The authors call for a larger study after raising this concern on neoatherosclerosis at 5 years after BVS 1.1 implantation as their study had only twenty patients with 22 lesions. Their study had a median follow up of 67 months and mean age of the patients was 69 years +/- 8 years.

Reference

  1. Moriyama N, Shishido K, Tanaka Y, Yokota S, Hayashi T, Miyashita H, Koike T, Yokoyama H, Takada T, Nishimoto T, Ochiai T, Tobita K, Yamanaka F, Mizuno S, Murakami M, Takahashi S, Saito S. Neoatherosclerosis 5 Years After Bioresorbable Vascular Scaffold Implantation. J Am Coll Cardiol. 2018 May 1;71(17):1882-1893.