Long term mortality similar for mechanical vs bioprosthetic valves in older patients

Long term mortality similar for mechanical vs bioprosthetic valves in older patients

Mechanical vs bioprosthetic valves in older patients: J Matthew Brennan, Fred H Edwards, Yue Zhao, Sean O’Brien, Michael E Booth, Rachel S Dokholyan, Pamela S Douglas, Eric D Peterson, DEcIDE AVR (Developing Evidence to Inform Decisions about Effectiveness–Aortic Valve Replacement) Research Team from Duke Clinical Research Institute [1] studied the Society of Thoracic Surgeons Adult Cardiac Surgery Database for those between sixty five and eighty years who underwent aortic valve replacement at six hundred and five centres in the nineteen nineties. There were over twenty four thousand who had undergone bioprosthetic implant while there a little less than fifteen thousand had a mechanical prosthesis. Both groups had similar age adjusted risk of death while the risk of reoperation and endocarditis was higher with the bioprosthetics. At the same time, the risk of stroke and bleeding were lower in those with bioprosthetic valves than mechanical valves.

Reference

1. J Matthew Brennan, Fred H Edwards, Yue Zhao, Sean O’Brien, Michael E Booth, Rachel S Dokholyan, Pamela S Douglas, Eric D Peterson, DEcIDE AVR (Developing Evidence to Inform Decisions about Effectiveness–Aortic Valve Replacement) Research Team, Long-Term Safety and Effectiveness of Mechanical versus Biologic Aortic Valve Prostheses in Older Patients: Results from the Society of Thoracic Surgeons (STS) Adult Cardiac Surgery National Database. Circulation. 2013 Apr 23;127(16):1647-55.