Off pump bypass less effective than on pump – ROOBY Trial

Off pump bypass less effective than on pump – ROOBY Trial

Off pump bypass less effective than on pump: ROOBY Trial conducted by Brack Hattler, John C Messenger, A Laurie Shroyer, Joseph F Collins, Scott J Haugen, Joel A Garcia, Janet H Baltz, Joseph C Cleveland Jr, Dimitri Novitzky and Frederick L Grover, the Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group randomized on pump bypass surgery versus off pump bypass surgery. Over two thousand and two hundred subjects were randomized between 2002 and 2007 [1]. All results were classified using FitzGibbon classification into: A=widely patent, B=flow limited and O=occluded. The definition of effective revascularization was to have FitzGibbon A quality graft to major diseased artery in all the territories with significant disease and the absence of new post anastomotic lesions. Lower FitzGibbon A patency rates were noted with off pump coronary artery bypass grafting (CABG) than on pump CABG for arterial grafts (85.8 percent versus 91.4 percent; P=0.003) and SVG (saphenous vein grafts) (72.7 percent versus 80.4 percent; P<0.001).

Reference

1. Brack Hattler, John C Messenger, A Laurie Shroyer, Joseph F Collins, Scott J Haugen, Joel A Garcia, Janet H Baltz, Joseph C Cleveland Jr, Dimitri Novitzky, Frederick L Grover, Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group. Off-Pump Coronary Artery Bypass Surgery Is Associated With Worse Arterial and Saphenous Vein Graft Patency and Less Effective Revascularization. Results From the Veterans Affairs Randomized On/Off Bypass (ROOBY) Trial. Circulation. 2012 Jun 12;125(23):2827-35.