Idarucizumab for reversal of direct thrombin inhibitor dabigatran Idarucizumab is a monoclonal antibody fragment used to reverse the anticoagulant effect of direct thrombin inhibitor dabigatran. RE-VERSE AD (Reversal
Clinical importance of LBBB Left bundle branch block (LBBB) is usually associated with structural heart disease, unlike right bundle branch block which may be seen without associated heart
HOST-EXAM trial HOST-EXAM (Harmonizing Optimal Strategy for Treatment of coronary artery diseases-EXtended Antiplatelet Monotherapy) trial was an investigator initiated, prospective, randomized, open label multi centre trial [1]. The
Identification of culprit vessel from ECG Identification of culprit vessel or infarct artery localization from ECG is useful during primary angioplasty. The initial diagnostic angiogram shot is taken
Athlete’s heart അത്ലറ്റിന്റെ ഹൃദയം एथलीट का दिल Athlete’s heart is hypertrophy (thickening of the walls) due to the constant training. The ideal method of differentiating this hypertrophy from
Left ventricular reverse remodeling Left ventricular remodeling which starts initially as a beneficial process becomes detrimental later on leading to progressive worsening of left ventricular dilatation and dysfunction.
Renal denervation for hypertension Renal denervation for hypertension, initially thought to be a promising procedure, went into disrepute after the publication of the SYMPLICITY HTN-3 trial [1]. But
GALACTIC-HF Trial: Omecamtiv mecarbil GALACTIC-HF trial evaluated omecamtiv mecarbil, a cardiac myosin activator in heart failure with reduced ejection fraction [1]. The study had 8256 patients which included
Echocardiographic assessment of LV diastolic function Though there are several parameters for evaluation of left ventricular diastolic function by echocardiography, the most commonly used are the pulsed Doppler
Non invasive cardiac output monitoring Conventionally, measurement of cardiac output was done invasively. Initially with dye dilution techniques and later by thermodilution techniques. Both needed pulmonary artery catheterization,
