All About Cardiovascular System and Disorders

Newer anti anginal drugs: ranolazine inhibits late sodium current, trimetazidine inhibits beta oxidation of fatty acids, nicorandil dilates coronary resistance vessels.

Myocardial oxygen consumption is the oxygen consumed by heart muscle and the determinants are intramyocardial wall tension, contractility and heart rate.

6 minute walk test is a simple test to estimate the functional capacity in patients who cannot perform a conventional exercise test like treadmill test.

ATP test is done to decide whether patients with syncope of unknown origin will benefit from cardiac pacing.

Discrete membranous sub aortic stenosis can be treated by transluminal balloon tearing of the membrane instead of open surgical resection.

Same day discharge if feasible is a welcome option for the patient, especially in elderly who are often afraid of staying in hospitals and ICUs.

Rivaroxaban reduced the risk of composite endpoint in ACS, but increased risk of major bleeding and intracranial hemorrhage, though not fatal bleeding.

Biodegradable polymer biolimus eluting stents are non inferior to durable polymer sirolimus eluting stents and had lower very late stent thrombosis.

Unlike in the case of torcetrapib, dalcetrapib did not increase the blood pressure.

ISAR-CABG trial: for de-novo saphenous vein graft lesions, drug eluting stents were better than bare metal stents.