Predisposition to statin adverse effects – Cardiology MCQ

Condition/s which predispose/s to statin adverse effects:

a) Impaired renal or hepatic function
b) History of previous statin intolerance or muscle disorders
c) Unexplained elevation of SGPT
d) All of the above
Correct answer: d) All of the above
In addition to these, age above 75 years, Asian ancestry and previous hemorrhagic stroke are potential conditions to considered while considering high intensity statin therapy with regard to predisposition for adverse effects. Concomitant usage of drugs likely to affect statin metabolism should also be considered.