Primary pericardial mesothelioma
Unlike the pleural mesothelioma, direct link to asbestosis in case of primary pericardial mesothelioma has not been established . It is a very rare malignant tumour of the pericardium with around 150 cases reported. Yet it represents half of primary pericardial tumours. It is a malignancy of the mesothelial cells lining the visceral or parietal pericardium.
Majority of cases occur between fourth and seventh decade and a male preponderance has been noted. They can present with large pericardial effusions which can be fatal . In general it is an aggressive disease with survival less than 6 months. In one case report, initial chemotherapy followed by radiotherapy was given. Still tumour progression was noted at 10 months after the end of radiotherapy and second line chemotherapy was given. Survival in this case was 16 months from diagnosis .
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