Ranolazine – Cardiology MCQ

Ranolazine is:
a) Inhibitor of late sodium current
b) I_f current inhibitor
c) Potassium channel opener
d) Calcium channel blocker
Correct answer: a) Inhibitor of late sodium current
In addition this ranolazine is a partial inhibitor of beta oxidation of fatty acids. These two mechanisms account for its anti anginal effect. Ranolazine is also increasingly being tried for its anti arrhythmic effect. In this respect it has historical similarity to amiodarone which was initially introduced as an anti anginal agent and later became known as a broad spectrum anti arrhythmic agent.