Stent thrombosis in the setting of surgery

Stent thrombosis in the setting of surgery

Stent thrombosis is a serious complication, which is more likely with drug eluting stents (DES) than bare metal stents (BMS). This is because the anti-mitotic drug eluting from the DES prevents endothelialization of the coronary artery to a longer than a bare metal stent, which gets endothelialized faster.

With newer generation drug eluting stents, the incidence of stent thrombosis is much lower.

Stent thrombosis commonly presents as cardiovascular mortality or as large nonfatal myocardial infarction, usually with ST elevation.
There are possibly dual reasons for stent thrombosis in the setting of a surgery – the withdrawal of protection from anti-platelet agents and the fact that surgery itself induces a prothrombotic state.