Disadvantage of using Fondaparinux as the sole agent in PCI

Disadvantage of using Fondaparinux as the sole agent in PCI

Catheter related thrombosis is higher with Fondaparinux unless supplemented with heparin. This is because of low anti-Factor IIa activity. Fondaparinux has relatively pure anti-Factor Xa activity. Unfractionated heparin has the best anti-Factor IIa activity.

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