AFFIRM on treatment analysis

AFFIRM Trial on treatment analysis

Stroke risk is increased risk 4-5 fold with atrial fibrillation. On treatment analysis of AFFIRM data found that only two markers of survival advantage was sinus rhythm and use of warfarin. They concluded that if a drug with less side effects for maintaining rhythm in AF is found, rhythm control would be superior to rate control. Original AFFIRM trial was an intention to treat analysis.