Anticoagulation for primary PCI – Cardiology MCQ

Which of the following should not be used as sole anticoagulant for primary percutaneous coronary angioplasty ?
 
a) Unfractionated heparin
b) Bivalirudin
c) Fondaparinux
d) None of the above
Correct answer: c) Fondaparinux
 
If Fondaparinux is used as the sole anticoagulant during primary PCI, there is a higher incidence of catheter thrombosis.
Unfractionated heparin is used in most cases, supplemented if needed, by glycoprotein IIb/IIIa receptor antagonist if needed in case of significant thrombus load. Some prefer Bivalirudin in cases with a higher bleeding risk instead of the above combination.

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